Pharmacokinetic Analysis of Cilostazol: A Comprehensive Study on AUC and Population Factors

Feb 10, 2026

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This study investigates the pharmacokinetics (PK) of Cilostazol, focusing on key parameters such as K-Betest AUCt, Cmax, and Tmax. Utilizing WinNonlin, we analyzed AUCinf, total clearance (CLtotal), elimination rate constant (Kel), half-life (t1/2), absorption rate constant (Ka), volume of distribution (Vd/F), and the ratio of AUCt to AUCinf. Additionally, we performed a population PK analysis using NONMEM to assess the impact of factors such as sex, weight, alcohol, and caffeine. Furthermore, PK/PD modeling was conducted using ADAPT for advanced PK data insights.

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Pharmacokinetic Analysis of Cilostazol: A Comprehensive Study on AUC and Population Factors

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