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African Prostate Tumor Biomarkers Biobank Study

This study aims to establish a biobank of prostate FFPE tissues in diverse African descent populations to evaluate tumor markers related to disease aggressiveness. The study will focus on various markers including TMPRSS2/ERG fusion proteins, infection/inflammation markers, miRNA, telomere dysregulation, and gene expression regulation. Working group leaders are located in Nassau, Bahamas, Philadelphia, USA, and Dakar, Senegal. Study initiated in December 2011.

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African Prostate Tumor Biomarkers Biobank Study

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  1. MADCaP Multilevel Determinants Working Group

  2. Tumor Biomarkers Working Group Aim 1. Establish a biobank of prostate FFPE tissues in geographically diverse African descent populations. Aim 2. Evaluate tumor markers in association with disease aggressiveness: -TMPRSS2/ERG and related fusion proteins -Markers of infection and inflammation -miRNA -Telomere dysregulation -Gene expression and regulation (methylation) Working Group Leaders: Jong Park, Robin Roberts (Nassau, Bahamas); Tim Rebbeck, Priti Lal, Mike Feldman (Philadelphia, USA); Serigne Gueye, Mohamed Jalloh, Sira Thiamm, Cheik Sy, Nafissatou Ba (Dakar, Senegal)

  3. Tumor Biomarker Studies December, 2011

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