Rhabdomyolysis The breakdown of skeletal muscle fibers causing myoglobin to be released into the blood stream which can lead to kidney damage. Stephanie Shinn Pd. 1 Bio.
A protein found in Cardiac and Skeletal muscles. • During exercise, it provides extra oxygen to the muscle to sustain activity. • When damage occurs, it goes into the bloodstream. • Kidneys are responsible for the removal of Myoglobin, and when there’s too much, it can severely damage them and induce disorders such as Rhabdomyolyis. What is myoglobin?
Traumatic • Electrical Injury • Burns • Heatstroke • Crush Injuries • Non-traumatic • Excessive Exercise • Some Medications (Statins) • Infections • Other Medical Or Genetic Disorders Causes
Abnormal Urine Color (Dark, red, cola colored). • Decreased Urine Production • General Weakness • Muscle Stiffness • Muscle Tenderness • Weakness of Affected Muscle • Unintentional Weight Gain • Joint Pain • Seizures • Swelling (Hands & Feet) • Trouble Breathing • Abnormal Heartbeat • Unexplained Bleeding Symptoms
Anyone can get Rhabdomyolyis! • Risk Increasers: • Alcoholism. • Drug Use (Cocaine, Amphetamines, Heroin, PCP). • Severe Exertion (Marathon Running, Calisthenics, etc). Prevalence
Consume fluids containing bicarbonate. • Through IV if necessary. • Prevents kidney damage. • Flushes out myoglobin. • Possible Kidney Dialysis. • Prescribed Diuretics or Bicarbonates. Treatments
Rhabdomyolysis is dangerous, and even fatalat its worst. • Always drink plenty of fluids after strenuous exercise or any activity that may have damaged the skeletal muscle to prevent myoglobin from entering the bloodstream and affecting your kidneys! Remember
PubMed Health • AANEM – Rhabdomyolysis • Medline Plus • PudMed Health – Myoglobin • Krames Patient Education Works Cited