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Personalized Medicines for Aging Populations

Personalized Medicines for Aging Populations. John Alam, MD Head of TSU Aging Sanofi R&D 12 December, 2011. Sanofi Aging R&D Strategy. Treatments for age-related chronic diseases such as Alzheimer’s, osteoarthritis, stroke recovery, and hearing loss

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Personalized Medicines for Aging Populations

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  1. Personalized Medicines for Aging Populations John Alam, MD Head of TSU Aging Sanofi R&D 12 December, 2011

  2. Sanofi Aging R&D Strategy • Treatments for age-related chronic diseases such as Alzheimer’s, osteoarthritis, stroke recovery, and hearing loss • Treatment of age-related syndromes such as chronic disabling pain, age-related muscle loss, and frailty • Preventive strategies for major age-related pathologic processes (novel dietary supplements or innovative uses of existing medicines)

  3. Healthy State Acute Illness Known Specific Cause Target Specific Cause Candidate Medicine

  4. Chronic Disorders of Aging Multi-morbidity – Multi-medications Increasing importance of social environment Senescence Disease 1 Disease 2 Disease n Geriatric Syndromes Health Issues (Disorders/ Diseases) Function & Structures (Deficiencies) Participation (Restrictions) Activities (Limitations) Environmental Factors Personal Factors

  5. Physical Activities Cognitive Stimulation Vaccines & Drugs Nutrition Educational & coaching programs Continuity of Care Home Services Geron- technologies Senescence Disease1 Disease2 Diseasen Geriatric Syndromes Health Issues (Disorders/ Diseases) Fonctions & Structures (Deficiencies) Participation (Restrictions) Activities (Limitations) Environmental Factors Personal Factors

  6. July 2003

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