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Synthesis of Pimprinine and Oxaprozin from Enamides: A Promising Approach for Anti-inflammatory Drugs

This presentation discusses the synthesis of Pimprinine and Oxaprozin from enamides as a method for developing effective anti-inflammatory drugs to treat osteoarthritis and rheumatoid arthritis. Previous work and two proposed routes are explored.

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Synthesis of Pimprinine and Oxaprozin from Enamides: A Promising Approach for Anti-inflammatory Drugs

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  1. Work Presentation Synthesis of Pimprinineand Oxaprozin from Enamides YunhuiZheng 2013.3.15 1

  2. Pimprinine 2

  3. 3

  4. 4

  5. 5

  6. Oxaprozin It is a non-steroidal anti-inflammatory drug, used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Previous work This work 6

  7. Route A 7

  8. Route B 8

  9. 9

  10. Thank you!

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