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Sentinel node procedure en neoadjuvante chemotherapie

Sentinel node procedure en neoadjuvante chemotherapie. Omgo E. Nieweg Maartje C. van Rijk Pieter J. Tanis Renato A. Vald és Olmos Emiel J.Th. Rutgers Hans L. Peterse Bin B.R. Kroon. Standaardokselklierdissectie achterwege gelaten na minder dan 10 procedures. chirurgen

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Sentinel node procedure en neoadjuvante chemotherapie

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  1. Sentinel node procedure en neoadjuvante chemotherapie Omgo E. Nieweg Maartje C. van Rijk Pieter J. Tanis Renato A. Valdés Olmos Emiel J.Th. Rutgers Hans L. Peterse Bin B.R. Kroon

  2. Standaardokselklierdissectie achterwege gelaten na minder dan 10 procedures chirurgen Nederland 43 % U.S.A. 31 % U.S.A. 55 % Schijven, Eur J Surg Oncol 2000; 26: 431-2 Lucci, 2nd Int. Sentinel Node Congress, Santa Monica, 2000 Zervos, Ann Surg Oncol 2001; 8: 7-12

  3. Axillair recidief patiënten Roumen (Br J Surg 2001; 88: 1639-43) 1 Schrenk (J Surg Oncol 2001; 77: 165-70) 0 Hansen (Arch Surg 2002; 137: 1131-5) 0 Torrenga (Eur J Surg Oncol 2002; 28: 304) 1 Guenther (Ann Surg Oncol 2002; 9 Suppl: S56) 1 Bedrosian (Ann Surg Oncol 2002; 9 Suppl: S57) 0 Chung (Am J Surg 2002; 184: 310-4) 3 Veronesi (N Engl J Med 2003; 349: 546-53) 2 Badgwell (Ann Surg Oncol 2003; 10: 376-80) 0 Reitsamer (Eur J Surg Oncol 2003; 29: 221-3) 0 Antoni van Leeuwenhoek ziekenhuis 2

  4. Sentinel node biopsie en neoadjuvante chemotherapie • stadiëring • prognostische informatie • voorkomen van onnodige okselklierdissectie • beoordelen effect chemotherapie • indicatie radiotherapie

  5. Sentinel node biopsie na neoadjuvante chemotherapie • identificatie 87 % (84 - 98 %) • foutnegatief 8 % (0 - 33 %)

  6. Sentinel node biopsie voor neoadjuvante chemotherapie patiënten aantal 17 identificatie 17 tumor + 6 okselklierdissectie bespaard 11 axillair recidief 0

  7. Conclusies theoretisch aantrekkelijker : sentinel node biopsie na neoadjuvante chemotherapie

  8. Conclusies theoretisch aantrekkelijker : sentinel node biopsie ná neoadjuvante chemotherapie voorzichtiger : sentinel node biopsie vóór neoadjuvante chemotherapie

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