1 / 35

Mapping your career with NIH

Mapping your career with NIH. Michael Sesma, Ph.D., NIMH Milton J. Hern á ndez, Ph.D., DLR, OEP NIH. Basic Advice for Mapping Your Career with NIH. Understand the NIH application process including the review process Understand the ICs and their goals

kineks
Télécharger la présentation

Mapping your career with NIH

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Mapping your career with NIH Michael Sesma, Ph.D., NIMH Milton J. Hernández, Ph.D., DLR, OEP NIH

  2. Basic Advice for Mapping Your Career with NIH • Understand the NIH application process including the review process • Understand the ICs and their goals • Each IC has a research training and career development program • Identify the grant programs offered by each IC • Make early contact with program officers • Find Mentors and Collaborators • Study successful grant applications • Only propose your best, creative ideas • Appropriate number of goals • Impact – now more important than ever • Include preliminary data if you have it • You won’t get a grant if you don’t apply

  3. R03 Diversity Supplements

  4. Training Grants (Ts) • NRSA- National Research Service Award • Legislated, program began in 1974 (P.L. 93-348) • Multi-slot awards • Domestic institutions only • Fund training programs for pre- and postdocs in any scientific area within our scientific mission • Can be basic or clinical • Trainees work in a mentor’s lab • MDs, PhDs, DVMs • Awards go the best training programs in the Nation

  5. Fellowships (Fs): • NRSA- National Research Service Award • Legislated, program began in 1974 (P.L. 93-348) • Individual awards under a mentor • Training can be at domestic or foreign institutions • Fund pre- and postdoc trainees in any scientific area within our scientific mission • Can be basic or clinical - most are basic • Most awardees are for Ph.D.s • F Kiosk: http://grants.nih.gov/training/F_files_nrsa.htm

  6. Career Development Awards (Ks) • Individual awards • Mechanisms for Basic and Clinical Investigators • Designed as awards for faculty investigators • Some mentored others not • Newer programs (K22 and K99/R00) are transition awards- these are for MDs and PhDs • K Kiosk: http://grants.nih.gov/training/careerdevelopmentawards.htm

  7. Training Grants • Some all predoc/some all postdoc • Most are a mixture of slots • Funds are mostly for tuition and trainees • Training Related Expenses may be used to defray costs such as staff salaries, equipment, research supplies, and other expenses directly related to the training program • Costs: • Tuition- 60% of requested tuition, capped at $16,000 ($21K for MD-PhD programs) • Stipends- $20,772 pre/ postdoc $36,996 (level 0)-$51,036 (level 7) • Training Related Expenses- $4,200 pre/$7,850 (post); both include health insurance • Travel- $400-$1000 • F&As- 8%

  8. F30s and F31s- Predoc Fellowships • Individual awards • Cannot change the scope, move fellowship, or change mentor without prior NIH approval! (They do anyway) • Predoctoral NRSA awards limited to 5 years total • Tuition- 60% of requested tuition, capped at $16,000 ($21K for MD-PhD programs) • Stipends- $20,772 pre • Training Related Expenses- $4,200 includes health insurance • Travel- $400-$1000 • F&As- 8%

  9. F32sPostdoc NRSA Fellowships • Postdoc only • Individual award • Cannot change the scope, move fellowship, or change mentor without prior NIH approval! (They do anyway) • NRSA Support for up to 3 years total • Stipends- $36,996 (level 0)-$51,036 (level 7) • Training Related Expenses- $7,850; includes health insurance • Travel- $400-$1000 • F&As- 8%

  10. F33sSenior Postdoc Fellowships • Not for postdocs who have been postdocs a long time • Used for associate or full professors who want support for a sabbatical • For MDs or PhDs • Few applicants - too little money • Stipend = $51,036 • Training Related Expenses - $7,850; includes health insurance • Travel- $400-$1,000

  11. Fellowship Review Criteria In addition to an Overall Impact score there are 5 Core Review Criteria for Fellowships. These are distinct from R-type award Core Criteria; criterion scores will be provided by the reviewers (1-9) • Fellowship Applicant • Sponsors, Collaborators, and Consultants • Research Training Plan • Training Potential • Institutional Environment & Commitment to Training

  12. K01Mentored Research Scientist Development Award • Support development experiences leading to research independence, training in new field or following hiatus in a research career (varies by IC) • MDs or PhDs • 3-5 years • Salary Cap varies by IC + FBs • Research Support: up to $50,000/yr (varies by IC) • F&As= 8% • IC contacts and policies: • http://grants2.nih.gov/grants/guide/pa-files/PA-10-056.html

  13. K02Independent Scientist Award • Often called Mid-career award; Best candidate is a “senior” assistant professor or “junior” associate professor • Close to or recently promoted and tenured • Must have independent grant support as PI, e.g., R01 • MDs (very few) and PhDs • Salary support only • Salary Cap varies by IC + FBs for up to 5 years • Gives up salary support from all other NIH grants! • Relatively few applicants • F&As= 8% • http://grants.nih.gov/grants/guide/contacts/parent_K02.html

  14. K08-Mentored Clinical Scientist Development AwardK23- Mentored Patient-Oriented Research Career Development Award • K08 - supports didactic study and mentored research for individuals with clinical doctoral degrees • K23 - for clinical/patient-oriented project • 3-5 yr award, varies by IC • Salary cap varies by IC + FBs • Research Support up to $50,000/yr (varies by IC) • F&As= 8% • For IC Contacts and policies • http://grants.nih.gov/grants/guide/contacts/parent_K08.html • http://grants.nih.gov/grants/guide/contacts/parent_K23.html

  15. K24Mid-Career Investigator Award in Patient-Oriented Research • Purpose: to provide support for clinician investigators to allow them protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for junior clinicians • 3-5 years • Typically MDs • Salary cap varies by IC + FBs • Research Support $25,000 - $50,000 (varies by IC) • F&As= 8% • http://grants.nih.gov/grants/guide/contacts/parent_K23.html

  16. K25Mentored Quantitative Research Development Award • For individuals from a quantitative background (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and engineering) who want to apply their expertise to a biomedical problem and are not already working in a health or disease related topic • 3-5 years • Salary cap varies by IC + FBs • Research Support: $20,000 - $50,000 (varies by IC) • F&As= 8% • http://grants.nih.gov/grants/guide/contacts/parent_K25.html

  17. K99/R00 Pathway to Independence Award • Supported by almost all ICs with variations* • Transition award for postdocs moving to assistant professor positions (tenure track or equivalent) • No Citizenship/Green Card requirement • K99 mentored phase (up to 2 years) • R00 independent phase (up to 3 years; 75% effort) • Requires mentor(s) • *Up to $90,000/yr total cost for K99 phase; 8% F&A • $249,000/yr total cost for R00 phase • http://grants.nih.gov/grants/guide/contacts/parent_K99_R00.html

  18. K22 Research Scholar Development Award • Offered by NCI, NHLBI, NIAID, NIAAA, NINR • Transition award for postdocs moving to positions of assistant professor • Two-phased application • Phase 1 • Scientific merit • No institution yet • If applicant gets a fundable score, they have a year to find a position as assistant professor • Phase 2 • Assistant Professor • Own lab • Significant start-up funds • Little teaching/ no administrative responsibilities • F&As= 8%

  19. K22 Transition award (postdoc-to-asst. professor) 2 yr award No mentored phase Awardee gets funds at the time of becoming asst. professor $250K + 8% F&A costs Total Cost= $270K K99/R00 Transition award (postdoc - to asst. professor) 3 year award only 2 yr mentored phase ($90K/yr TC) Awardee becomes asst. professor- R00 not peer reviewed 3 yr independent R phase ($249K/yr TC) Total Cost= $574K but note TC in R00 phase K22 and the K99/R00 Award Main features

  20. Career Award Review Criteria In addition to an Overall Impact score there are 5 Core Review Criteria for K-award applications that are distinct from R-type award Core Criteria; criterion scores will be provided by the reviewers (1-9) • Candidate • Career Development Plan/Career Goals & Objectives/Plan to Provide Mentoring • Research Plan • Mentor(s), Consultants(s), Collaborator(s). • Environment and Institutional Commitment to the Candidate

  21. New NIH PolicyEncourage New Investigator Applications for the R01 • In recent years the use of Small Grants (R03) and the NIH Exploratory /Developmental Research Grant (R21) has increased : • New Investigator policies are limited to applications for Traditional Research project grant (R01) support. Accordingly, the NIH is strongly encouraging New Investigators, particularly Early Stage Investigators, to apply for R01 grants when seeking first-time NIH funding. % First-Time Investigators

  22. Why an R01?It is the Gold Standard Grant! • The Research Project Grant (R01) is the original and historically oldest grant mechanism used by NIH. The R01 provides support for health-related research and development based on the mission of the NIH. • R01s can be investigator-initiated or can be in response to a program announcement or request for application. • The R01is an award made to support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing the investigator's specific interest and competencies, based on the mission of the NIH.

  23. Are You a “New Investigator”? • Definition:New Investigator (NI) is a PD/PI who has not yet competed successfully for a substantial NIH research grant (Except for R03, R15, R21 or mentored K awards) • Definition:Early Stage Investigator (ESI) is a NI who is within 10 years of completing the terminal research degree or is within 10 years of completing medical residency (or equivalent) • NI/ESI receive special considerations during peer review and IC funding decisions • Resource web site with further information grants1.nih.gov/grants/new_investigators grants.nih.gov/grants/guide/notice-files/NOT-OD-08-121.html

  24. New/Early Stage Investigators PURPOSE Encourage and accelerate earlier transition to research independence (i.e., first R01) Counter trend of increasing time spent in training phase of career Strongly encourage New Investigators, particularly ESIs, to apply for R01 grants when seeking first-time NIH funding  Identification of NI/ESI Applicants

  25. New/Early Stage Investigator ESI/NI Applications will be identified to reviewers so that appropriate consideration of career stage can be applied during review. Apprise NIH staff of ESI/NI status, which will be considered when applications are selected for award Support New Investigators (majority expected to be ESIs) at success rates equivalent to that of established investigators submitting new applications  For multiple PD/PI applications, all PD/PIs must meet requirements for ESI status to receive consideration during review ESIs/NIs are eligible for the Shortened Review Cycle option (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-083.html ) New and Early Stage Investigator Policies

  26. New/Early Stage Investigators Information Sources • NOT-OD-08-121 (09/26/2008) - Encouraging Early Transition to Independence: Identifying ESIs http://grants1.nih.gov/grants/guide/notice-files/not-od-08-121.html • NOT-OD-09-013 (09/31/2008) – Revised New and Early Stage Investigator Policies http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-09-013.html • NOT-OD-09-034 (12/31/2008) – ESI Policies: Requesting an Extension of the ESI Period http://grants.nih.gov/grants/guide/notice-files/NOT-OD-09-034.html • FAQs:http://grants.nih.gov/grants/new_investigators/investigator_policies_faqs.html

  27. Other NIH Awards for New Investigators Support exceptionally innovative research with potential for significant impact Launched in 2007 Open to new investigators within ten years of their terminal degree Appointment at US institutions Commit at least 25% effort Up to $1.5 million over 5 years (direct costs) Abbreviated application Preliminary data optional Review focus on innovation and creativity, scientific impact Number of Applications and awards 2007 2150 30 2008 579 31 2009 419 ? + ARRA http://nihroadmap.nih.gov/newinnovator/

  28. Loan Repayment Programs An Overview Division of Loan Repayment (DLR) Office of Extramural Research/Office of Extramural Programs National Institutes of HealthU.S. Department of Health and Human Services Milton Hernández, Ph.D. Director NIH Division of Loan Repayment, OEP

  29. Program Overview • NIH Loan Repayment Programs (LRPs) • Vital component of our Nation's efforts to attract and retain highly qualified health professionals • Working in priority areas • To build a research workforce that will meet our future national needs 30 30

  30. Loan Repayment Programs Intramural Programs (1989 to Present) AIDS Research LRP (1989) Clinical Research LRP for Individuals from Disadvantaged Backgrounds (1994) General Research LRP (1996) Extramural Programs (2001 to Present) Contraception & Infertility Research LRP (1997) Health Disparities Research LRP (2001) Clinical Research LRP for Individuals from Disadvantaged Backgrounds (2001) Clinical Research LRP (2002) Pediatric Research LRP (2002) 31

  31. LRPs- How do they work? • Up to $35,000 per year in loan repayment depending on debt level • Coverage of Federal, state and local taxes resulting from the NIH LRP • 2 year initial contracts with 1 – 2 year competitive extension contracts

  32. Individual LRP Funding History FY 2002 thru FY 2008 33

  33. Educational Debt, by Degree Type Trends Analysis, FY03-FY07 Among LRP applicants, academic doctorates have a higher debt load than recent PhD graduates, and physician doctorates have a lower debt load than recent MD graduates. *Source: Survey of Graduates, American Association of Medical Colleges (2001). †Source: Survey of Earned Doctorates, National Science Foundation (2003). 34

  34. LRP Evaluation Conclusions: • LRPs attract young scientists early in their careers- average age is 35 • Applicants have considerable educational debt • Women, MDs, and PhDs are adequately represented in applicant and awardee pools • LRP awardees receive more RPGs than unsuccessful applicants • But LRP awardees are not quite as successful as K awardees in receiving RPGs

More Related