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Wild Type Drosophila

Wild Type Drosophila. Ommatidium. 8 Photoreceptor cells (R1-R8) 4 Cone cells (secrete lens) 8 Pigment cells. Wild Type Eye Phenotype. Eyeless Mutant Phenotype (hypomorphic allele). Paired Domain Protein. DNA. Figure 1A. Gal4 Enhancer-Trap Method. LacZ. No Transcription of LacZ.

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Wild Type Drosophila

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  1. Wild Type Drosophila

  2. Ommatidium 8 Photoreceptor cells (R1-R8) 4 Cone cells (secrete lens) 8 Pigment cells

  3. Wild Type Eye Phenotype

  4. Eyeless Mutant Phenotype (hypomorphic allele)

  5. Paired Domain Protein DNA

  6. Figure 1A Gal4 Enhancer-Trap Method LacZ No Transcription of LacZ

  7. Figure 1A Gal4 Enhancer-Trap Method LacZ Enhancer that controls expression in specific tissues

  8. Figure 1A Gal4 Enhancer-Trap Method LacZ Tissue-specific Expression of Gal4 Tissue-specific Expression of LacZ

  9. Figure 1 Eye-Antennal disc wing disc leg disc

  10. Figure 1A Gal4 Enhancer-Trap Method LacZ Enhancer that controls expression in imaginal disc cells Transcription of LacZ in imginal disc cells

  11. Figure 1A Enhancer that controls expression in imaginal disc cells Transcription of eyeless in imginal disc cells

  12. Figure 2

  13. Figure 3

  14. Paired Domain Protein DNA Drosophila ey, mouse Pax-6 (sey) and Human Pax-6 (Aniridia) genes are ~ 94% similar in Paired domain

  15. Ectopic Expression of Mouse Pax-6 Gene Pax-6 Enhancer that controls expression in imaginal disc cells Transcription of Pax-6 in imginal disc cells

  16. Figure 5 Ectopic Expression of Mouse Pax-6 Gene

  17. Aniridia -- Human Pax-6 Mutation Absence of the iris

  18. Xenopus Oocyte Animal Pole Vegetal Pole

  19. Xwnt-11 mRNA Localization Xwnt-11 is Drosophila wingless homogue

  20. Ventralized Normal

  21. Embryo Grafting Experiment

  22. Goosecoid Protein Expression

  23. Embryo Grafting Experiment Inject mRNAs For Chordin etc.

  24. Formation of ventral structures

  25. Normal Dorsalized

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