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Minnesota Sleep Society 4 th Annual Meeting

Minnesota Sleep Society 4 th Annual Meeting. Jeffrey Kotulski , D.O. Functional Medicine/Orthomolecular Medicine. Linus Pauling. Abram Hoffer. Functional Medicine Matrix. Obesity. “ Diabesity ” – Mark Hyman, M.D. Obesity: Why are men getting pregnant?

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Minnesota Sleep Society 4 th Annual Meeting

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  1. Minnesota Sleep Society4th Annual Meeting Jeffrey Kotulski, D.O.

  2. Functional Medicine/Orthomolecular Medicine Linus Pauling Abram Hoffer

  3. Functional Medicine Matrix

  4. Obesity • “Diabesity” – Mark Hyman, M.D. • Obesity: Why are men getting pregnant? Author: Alexander Schauss, Ph. D • Wheat Belly Author: William Davis, M.D.

  5. Economics • 1960 - $0.25 of every dollar earned spent on food • 2010 - $0.08 of every dollar earned spent on food • 1960 - $0.05 of every dollar earned spent on health care • 2010 - $0.22 of every dollar earned spent on health care

  6. HPA Axis Issues • Cortisol DHEA • Cortisol 5 HTP Melatonin Insomnia Depression • Cortisol Muscle Mass (Sarcopenia) Glucose Insulin Resistance

  7. HPA Axis • Increased cortisol leads to increased consumption of carbohydrates • This leads to insulin resistance & cortisol resistance

  8. HPA Axis • Cortisol Resistance • A phenomena of the last decade. The anti-inflammatory properties are negated, however, the catabolic changes persist. • Stress = Inflammation

  9. “Direct inhibitory effects of melatonin upon several ACTH responses in the human adrenal gland.” Hormone Metabolism Res., 2011, May, 43 (5): 337-42.

  10. What is the Skinny on High Fructose Corn Syrup? • There is no skinny, it’s all FAT!

  11. Insomnia • Nocturnal melatonin production is significantly diminished in insomnia patients. - Psychology Res. 2002, Dec. 12; 113 (1-2): 17 - 27

  12. Where does hyperinsulinemia come from? 1. Genetics – insulin gene expression 2. Epigenetics 3. Social environment, cortisol 4. Exercise environment 5. Food environment • High fructose, low fiber

  13. Fructose Is Not Glucose • Fructose is 7 x more likely to form advanced glycation end-products (AGES) • Acute fructose does not stimulate insulin • Fructose does not suppress grehlin • Chronic fructose exposure promotes metabolic syndrome • Fructose: “It’s alcohol without the buzz.” -Gaby, Alterative Medicine Reviews, 2005 - Lustig, OrthoMolecular conference, 2013

  14. Fructose • Of the 600,000 items in the American food supply, 80% have added sugar (sucrose, HFCS). • Our food environment is “fructosified.”

  15. What About Gluten? (another day) • Wheat is a very unusual carbohydrate • Amylopectin A – • Spikes blood sugars after consumption more so than consuming table sugar.

  16. Examples from the Farm • Cows: THEN lifespan of 10 – 12 years NOW lifespan of 5 years • Chickens: THEN standing NOW siting The answer is…. it’s the grains.

  17. What Can We Do? • Doctors Food Project - Robert Lustig, M.D.

  18. Therapeutic Lifestyle Changes

  19. Biochemical Individuality Roger J. Williams, Ph.D.

  20. Fit By Design • Genetic testing using the following genes: • FABP2 • ADRB2 • ADRB3 • PPARG • Outcome of genetic analysis allows a personalized plan for long-term health.

  21. Genetics

  22. Jeffrey Kotulski, D.O.45 Teton LaneMankato, MN 56001(507) 388-7488

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