1 / 7

Action Potential Types

Action Potential Types. Fast- and Slow Response Action Potentials. Slow response: Ionic currents. Why slow response?. High dv/dt: >200 V/s High conduction velocity: 1-4 m/s Specific drug sensitivity: sodium channel blockers – (lidocaine) and tetrodotoxin. Low dv/dt: < 20 V/s

lilah-pratt
Télécharger la présentation

Action Potential Types

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Action Potential Types

  2. Fast- and Slow Response Action Potentials

  3. Slow response: Ionic currents Why slow response?

  4. High dv/dt: >200 V/s High conduction velocity: 1-4 m/s Specific drug sensitivity: sodium channel blockers – (lidocaine) and tetrodotoxin Low dv/dt: < 20 V/s Low conduction velocity: 0.02-0.05 m/s Specific drug sensitivity: calcium channel blockers – nifedipine, verapamil Spontaneous phase 4 depolarization Fast response: Atria Slow response: Ventricles, Purkinje Fibers. SAN, AVN

  5. Automaticity Pacemakers hierarchy: SAN,AVN, Purkinje fibers

  6. Why are fibers of the conducting system automatic? Membrane potential of SA nodal cells

  7. Pacemaker Frequency - Mechanisms

More Related