1 / 18

Johns Hopkins CPC4

Biopsy never diagnostic. Always revisit diagnosis or consider additional pathologic processes when either clinical course or clinical manifestations deviate from the expected or the typical.Consider:Not sarcoidosis Sarcoidosis plus independent process-e.g. infection, PE, CHFSarcoidosis plus associated process- e.g. CVID, CTD, othersTreatment effectsRare manifestations of sarcoidosis do occur.

lorant
Télécharger la présentation

Johns Hopkins CPC4

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

    1. Johns Hopkins CPC#4 David R. Moller, M.D. Johns Hopkins University Baltimore, USA

    14. Sarcoidosis Associated Pulmonary Hypertension Pulmonary hypertension prevalence 6% unselected pulm sarcoidosis patients 50% patients with dyspnea disproportionate to PFTs 70-80% in advanced lung disease Higher when measuring exercise induced pulm htn Multiple potential mechanisms Bronchovascular distribution of inflammation Advanced fibrocystic lung disease (loss of pulmonary capillary bed) Extrinsic compression of pulmonary arteries by LN, mediastinal fibrosis Cardiac sarcoidosis with systolic, diastolic dysfunction Hypoxic vasoconstriction Primary pulmonary vascular involvement (granulomatous arteritis) Veno-occlusive disease (rare)

    16. Cardiac Sarcoidosis: Clinical Manifestations Common Arrhythmias Heart block/conduction defects Congestive heart failure Sudden death

More Related