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Gene Deletions and Mutations in Clear Cell Renal Cell Carcinoma

Explore deletions and mutations of VHL, PBRM1, BAP1, and SETD2 genes on chromosomal locus 3p in clear cell renal cell carcinoma. Inspired by research from the American Association for Cancer Research.

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Gene Deletions and Mutations in Clear Cell Renal Cell Carcinoma

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  1. Figure 3 Deletions and mutations of VHL, PBRM1, BAP1 and SETD2 genes on chromosomal locus 3p Parts of this figure are adapted with permission from the American Association for Cancer Research: Duns, G. et al. Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma. Cancer Res. 70, 4287–4291 (2011) Larkin, J. et al. (2012) Epigenetic regulation in RCC: opportunities for therapeutic intervention? Nat. Rev. Urol. doi:10.1038/nrurol.2011.236

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