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Breast cancer

Breast cancer. Prof.Nazem shams. IS IT A SERIOUS PROBLEM ??. Breast findings. Anatomy. Types of breast cancer. In situ Intraductal (DCIS) Intralobular (LCIS) Invasive Infiltrating ductal carcinoma Tubular carcinoma Medullary carcinoma Mucinous carcinoma. Presentation :.

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Breast cancer

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  1. Breast cancer Prof.Nazem shams

  2. IS IT A SERIOUS PROBLEM ??

  3. Breast findings

  4. Anatomy

  5. Types of breast cancer In situ • Intraductal (DCIS) • Intralobular (LCIS) Invasive • Infiltrating ductal carcinoma • Tubular carcinoma • Medullary carcinoma • Mucinous carcinoma

  6. Presentation :

  7. CANCER BREAST Skin manifestations: 1) Skin dimpling, Tethering & Puckering:- 2) Skin fixation, ulceration & fungation 3) Nipple retraction: 4) Paget's disease of nipple 5) Peau d’orange: 6) Cancerous satellite nodules (late sign) 7) Cancer en cuirasse (very late sign) 8) Mastitis carcinomatosa 9) Malignant edema of upper limb (brawny arm) 10) Dilated veins

  8. CYSTSARCOMA PHYLLOIDE TUMORS

  9. dimpling

  10. Nipple retraction

  11. Paget disease

  12. Paget disease

  13. Eczema

  14. Peau d’orange

  15. ulceration & fungation

  16. Mastitis carcinomatosa

  17. satellite nodules

  18. Cancer en cuirasse

  19. edema of upper limb

  20. Winging of the scapula

  21. Risk factors of breast cancer

  22. Breast cancer pathology

  23. Tx No evidence of primary tumor Tis Carcinoma in situ T1 Tumor 2cm or < T2 2 to 5 cm T3 T> 5cm T4a extension to chest wall T4b edema (including peau d’orange),ulceration of skin,satellite nodules T4c T4a + T4b T4d Inflammatory carcinoma

  24. N0 no regional lymh node met. N1 Movable ipsilateral axillary l.nod. N2 Fixed ipsilateral axillary lymph n. or İnternal mammary lymh nodes N3 -İpsilateral supraclavicular l.n. -Fixed ipsilateral axillary lymph n. and İnternal mammary lymh nodes -İpsilateral infraclavicular l.n.

  25. M0 M1

  26. Stage 1 Tumor < 2.0 cm in greatest dimension No nodal involvement (N0) No metastases (M0)

  27. Stage II Tumor > 2.0 < 5 cm or Ipsilateral axillary lymph node (N1) No Metastasis (M0)

  28. Stage III Tumor > 5 cm (T3) or ipsilateral axillary lymph nodes fixed to each other or other structures (N2) involvement of ipsilateral internal mammary nodes (N3) Inflammatory carcinoma (T4d)

  29. Stage IV (Metastatic breast cancer) Any T Any N Metastasis (M1)

  30. INVESTIGATIONS :

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