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GPCR-PKA-CREB

GPCR-PKA-CREB. Activation of GPCR generates cAMP. AC. AC. Cell membrane. cAMP. g. a. a. b. GTP. GDP. ATP. GTP. cAMP. cAMP. cAMP. cAMP. cAMP activates PKA. CREB binds CRE. PKA c. cAMP. PKA c. PKA R. PKA R. PKA R. PKA R. PKA c. Nucleus. P. P. CRE.

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GPCR-PKA-CREB

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  1. GPCR-PKA-CREB Activation of GPCR generates cAMP. AC AC Cell membrane cAMP g a a b GTP GDP ATP GTP

  2. cAMP cAMP cAMP cAMP cAMP activates PKA. CREB binds CRE. PKAc cAMP PKAc PKAR PKAR PKAR PKAR PKAc Nucleus P P CRE Gene Transcription CREB

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