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Explore the intricacies of detecting neurotransmitters using cutting-edge electrochemical measurements. This comprehensive guide covers design, testing, and applications of various detection methods. Dive into the world of electrode interfaces, chemical reactions, and electron transfers to enhance your understanding of neuroscience.
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Neurotransmitters and their Detection • Introduction • Design • Testing • Application • Conclusion
Electrochemical Measurements • Introduction • Design • Testing • Application • Conclusion
Electrode Bulk solution Solution Osurf Obulk O’ O’ads ne− CURRENT R’ads Osurf Rbulk O’ Adsorption/Desorption Chemical reaction Electron transfer Mass transfer Overall Electrochemical Reaction • Introduction • Design • Testing • Application • Conclusion
VREDOX Multiplexed digital bitstream Analog to Digital Convertor (ADC) IIN 1 Register Analog to Digital Convertor (ADC) IIN 2 Register …. …. …. • Introduction • Design • Testing • Application • Conclusion Conceptual VLSI Design • Why VLSI ? • Multichannel • Low power • Integration with microfabricated sensors • Implantable • ‘Black box’ design -
Difference Integrator Comparator Latch ∫ Bitstream D Q IIN CLK 1 bit DAC IREF A {+1, −1} _ + D ADC:First order Delta-Sigma Modulator • Introduction • Design • Testing • Application • Conclusion • Why ΔΣ convertor ? • Low frequency of IIN • Bandwidth Resolution tradeoff • High oversampling ratio (OSR) • Noise shaping by OSR A problem: the average output level at the 1 bit DAC must be of the same order as the input signal level. Thus a fixed IREF cannot handle widerange IIN
Novel ΔΣ Modulator with time modulated feedback • Introduction • Design • Testing • Application • Conclusion
Introduction • Design • Testing • Application • Conclusion Clock Generation
Introduction • Design • Testing • Application • Conclusion System Block Diagram
Introduction • Design • Testing • Application • Conclusion VLSI Chip Micrograph