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Understanding Hemolytic Anemia and Related Blood Disorders: Causes and Implications

This review covers essential aspects of hemolytic anemia and other blood disorders, including their causes, types, and effects on red blood cells (RBCs). It highlights different forms of anemia such as pernicious anemia, caused by a lack of intrinsic factor vital for vitamin B12 absorption, and aplastic anemia, resulting from bone marrow damage. The review also discusses thalassemia, characterized by reduced hemoglobin and RBC count, and polycythemia, marked by excessive RBC production. Additionally, it provides insights into sickle cell anemia, a hereditary condition affecting blood shape and function.

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Understanding Hemolytic Anemia and Related Blood Disorders: Causes and Implications

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Presentation Transcript

  1. Review - Anemias/WBCs

  2. Hemolytic Anemia • Arrows indicate cells being destroyed; • Acquired (thru certain chemicals) or inherited

  3. Pernicious Anemia • Pernicious anemia is caused by a lack of intrinsic factor • Intrinsic factor is a protein made in the stomach. It helps your body absorb vitamin B12, necessary for normal RBC production; RBCs are larger & form chains

  4. Aplastic Anemia • Aplastic anemia develops when damage occurs to your bone marrow, slowing or shutting down the production of healthy RBCs • May be from radiation, toxic chemicals or certain drugs

  5. Thalassemia • Reduced hemoglobin and fewer red blood cells than normal. The genes that code for hemoglobin are missing or mutated.

  6. Polycythemia • The overproduction of red blood cells; may be 6 to 9 million erythrocytes per cubic millimeter of blood

  7. Sickle Cell anemia • Hereditary

  8. Identify this WBC

  9. Identify this WBC

  10. Identify this WBC ↓

  11. Identify ↙

  12. Identify

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