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Introduction to Bio-Informatics

Bioinformatics emerged in the mid-1980s to analyze biological sequence data using computer applications. It bridges biology and computer science, focusing on protein structures, DNA sequences, and gene expression. Key resources include the RCSB Protein Data Bank and the National Center for Biotechnology Information (NCBI), which offer tools for mapping and analyzing gene functions. Explore the human genome project and learn about functional genomics, artificial chromosomes in yeast and bacteria, and access molecular biology primers for deeper understanding.

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Introduction to Bio-Informatics

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  1. Introduction to Bio-Informatics

  2. Bio-Informatics • mid-1980s: analysis of biological sequence data • Lately: the computer applications in biological sciences

  3. Protein • Http://www.rcsb.org/ • Search for PBD id 1tfd • 3D structure • a.a. sequence

  4. DNA • National Center for Biotechnology Information (NCBI) http://www.ncbi.nlm.nih.gov/Sitemap/index.html • Mapping • Gene expression - Functional genomics • Sequence • Artificial Chromosome • Yeast Artificial Chromosome • Bacteria Artificial Chromosome

  5. Homework • Molecular primer http://www.ncbi.nlm.nih.gov/About/primer/index.html • Human genome project tour http://www.ncbi.nlm.nih.gov/Tour/

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