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Chemistry and Biochemistry Part 7. For Advanced Diploma students of the WEA Hunter Academy of Complementary Health. Chapter 14. Metabolism and its control: chemistry of the cell. Metabolism. The sum of all reactions in a cell. Reactions either break things down, or build things up
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Chemistry and BiochemistryPart 7 For Advanced Diploma students of the WEA Hunter Academy of Complementary Health (c) WEA Hunter Academy of Complementary Health. Created by John Radvan. Reproduction or transmission without the express permission of the author is prohibited.
Chapter 14 Metabolism and its control: chemistry of the cell
Metabolism • The sum of all reactions in a cell. • Reactions either break things down, or build things up • Multiple reactions are a pathway (getting from A to B) • If the sum pathway leads to a breakdown of a substance into energy, that is catabolism • If the sum pathway leads to the build up (synthesis) , that is anabolism
Metabolic Pathways • Reactions in a metabolic pathway are enzyme-catalysed • They have varying shapes and branches. • Look at all the figures on page 160 for examples • Note the ‘most important’ types of reactions listed under ‘Understanding metabolism’ on page 161. • It’s important to note, that intermediate products can sometimes be shunted into another pathway. Many pathways are linked this way.
Remarkable Metabolism • Look at the diagram on page 162-163 • The cell is remarkable, all these reactions are going on at once • Biochemistry is about studying these reactions, we will obviously only study a small number of these in this course
Regulation • Read the section under ‘Metabolic Regulation’ on page 164-165. Make sure you list and understand the different ways that metabolism can be regulated.
ATP, NAD and coenzymes • The rest of this chapter is very important. Please make sure you read through pages 165-167. Note particularly the definitions of each of the ‘players’ in metabolism. • Define them all, write out their long names, look at how they are formed and used • All of these molecules will play some part in the metabolic pathways that we are going to study in coming weeks.