1 / 52

NMR Spectroscopy: Understanding Chemical Shifts and Couplings

Explore the principles of NMR spectroscopy, focusing on chemical shifts, coupling patterns, and correlation. Learn about 13C, 1H, 19F, and 31P NMR, coupling constants, solvent effects, and more. Ideal for students and researchers in chemistry.

mflaherty
Télécharger la présentation

NMR Spectroscopy: Understanding Chemical Shifts and Couplings

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 13C NMR • C=O • CN

  2. Bromophenoles

  3. Operating frequencies

  4. Chloroform

  5. 13C Correlation Chart

  6. 1H Chemical shift overview

  7. Carbon-proton correlation

  8. Typical 13C Chemical shifts

  9. Carbonyl chemical shifts

  10. Substituent effects for alkanes

  11. Substituent increments for benzene derivatives

  12. Proton coupled spectrum

  13. Proton decoupled spectrum

  14. Pulse scheme

  15. T1 relaxation times

  16. T1 Relaxation times

  17. Off-resonance decoupling

  18. DEPT

  19. Equivalent carbons

  20. Monosubstituted benzene

  21. Disubstituted benzenes

  22. Solvent peaks

  23. Coupling patterns for spin 1 nuclei

  24. 1H spectrum of deuteroacetone

  25. Couplings to other nuclei • 19F • 31P • 13C?

  26. C-F couplings

  27. C-P couplings

  28. 13C paracetamol

  29. Coupling constants • One bond 1J • Two bond (geminal) 2J • Three bond (vicinal) 3J • Long range nJ

  30. One-bond couplings

  31. Two-bond coupling constants

  32. 2J • Ring size

  33. HCH angle dependence 2J

  34. Karplus curve (3JH,H)

  35. 3J(H,H)

  36. 3J

  37. Solvent signals

  38. Problem solving

More Related