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Components of addiction:

Dr. Adair, Is Marijuana really addictive? J. Randle Adair, D.O., Ph.D. Diplomate , American Board of Internal Medicine Certified, American Society of Addiction Medicine CAPTASA 2014. Components of addiction:. Use Abuse Tolerance Continued use despite consequences

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Components of addiction:

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  1. Dr. Adair, Is Marijuana really addictive?J. Randle Adair, D.O., Ph.D.Diplomate, American Board of Internal MedicineCertified, American Society of Addiction MedicineCAPTASA 2014

  2. Components of addiction: • Use • Abuse • Tolerance • Continued use despite consequences • Presence of a defined set of symptoms upon cessation

  3. The Cannabis Withdrawal Scale development: Patterns and predictors of cannabis withdrawal and distress.Allsop, DJ, et al., 2011. Drug and Alcohol Dependence, 119: 123-129

  4. Background: • 160 million current users worldwide • 2.1 million new users annually • 10% of users will become dependent • 1:2 odds of dependence with daily users

  5. Participants (n = 49 completed): • Inclusion criteria: • Usage 5 or more days/week in past 3 months • Cannabis dependence (DSM IV) • Previous experience of at least one withdrawal symptom • Willingness to quit for 2 weeks

  6. Method: • Baseline assessment • One week daily smoking • Quit session • CWS questionnaire daily (26 items) • Urine sampling

  7. Results:

  8. Results:

  9. Consistent Findings:(in descending order) • Sleep disturbance items (highest validity) • Angry outbursts • Feeling irritated • Physical tension • Nausea • Restlessness • Nervousness • Cravings • Depression • Loss of appetite • Headaches • Stomach ache • Intensity of withdrawal was lessimportant than degree of associated distress

  10. Conclusion: • Yes! There is a withdrawal syndrome! • …….and it helps drive addiction!

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