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Pathogenic Microbiology

Pathogenic Microbiology. Bacterial Laboratory Acquired Infections . 76% of exposures occurred in clinical labs; 6% in vaccine manufacturing facilities; 8% in research labs.

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Pathogenic Microbiology

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  1. Pathogenic Microbiology

  2. Bacterial Laboratory Acquired Infections • 76% of exposures occurred in clinical labs; 6% in vaccine manufacturing facilities; 8% in research labs. • Exposure modes: 60% inhalation, other exposure modes included ingestion (intentional, poor technique such as mouth pipetting, smoking and eating in the lab) and secondary transmission.

  3. Viral Laboratory Acquired Infections • >70% associated with research labs; 32% of all viral LAIs associated with animals • 18% of total were Hantavirus; of these, 8% were working with known infectious material or rodents - others thought they were working with uninfected rodents • 16% were in clinical labs; rest were in production or field work • Major exposure modes: inhalation, percutaneous (especially from animals)

  4. Rickettsial Laboratory Acquired Infections • All rickettsial LAIs were associated with research laboratories • 95% of overt infections were by Coxiella burnetii; remainder were Murine typhus • All Q fever cases by inhalation; all infected staff worked with or were in close proximity to sheep • Remaining cases were by percutaneous, inhalation, mucous membrane or unknown exposure modes

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