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Comprehensive Guide to NIH Grant Proposal Submission and Budgeting

This detailed guide provides essential information for researchers preparing NIH grant proposals. Key topics include understanding the types of proposals such as unsolicited, solicited, and investigator-initiated research. It highlights the importance of carefully reviewing guidelines, notes on funding limits, page limits, and eligibility requirements. Budget basics are also covered, detailing direct costs, indirect costs, and variations in budget formats. Researchers will find helpful links to funding opportunities and submission policies to ensure compliance and clarity in their applications.

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Comprehensive Guide to NIH Grant Proposal Submission and Budgeting

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  1. ORA Review Alex Galea Assistant Director

  2. Grant Instructions: RFA or PA • Read through the guidelines carefully • Make notes on specifications in the announcement, such as: • Funding limits • Page limits • Eligibility • NIH Office of Extramural Research http://grants.nih.gov/grants/oer.htm Search for: • Funding opportunities • Forms & Applications • Due dates and Submission policies, etc.

  3. Types of Proposals • Unsolicited Proposal • Investigator-Initiated Research • Submitted according to sponsor’s broad guidelines • Funding arrangement is usually a grant • Standard due dates by cycle • Parent Funding Opportunity Announcements (FOA) • Examples: • PA-13-302 = Research Project Grant (Parent R01) • PA-14-015 = NRSA Training Grant (Parent T32) • PA-14-077 = Admin Supplement to Existing NIH grant (Parent Admin Supp) • http://grants.nih.gov/grants/guide/parent_announcements.htm

  4. Types of Proposals • Solicited Proposal • Submitted in response to a specific work statement from the sponsor • Request for Application (RFA) • Solicits grant or cooperative agreement applications • Well-defined scientific area to accomplish specific program objectives • Indicates amount of funds, number of awards, and standard due dates • Request for Proposal (RFP) • Sponsor solicits a response to award a contract • Research meets a specific need for sponsor’s direct benefit • Single application receipt date

  5. Standard Receipt Dates for NIH • http://grants.nih.gov/grants/funding/submissionschedule.htm

  6. Budget Basics • Direct Costs • Facilities and Administrative (F&A) Costs • Indirect Costs • Total Costs • Modified Total Direct Costs (MTDC) • Total Direct Costs (TDC)

  7. Basic Expenditure Considerations • Allowable • Cost item meets sponsor requirements • Allocable • Particular cost item can be specifically identified with the project or can be clearly allocated to the project • Reasonable • Would a prudent person have incurred the expense under the circumstances? • Is the item necessary for the project?

  8. Two Distinct Budget Formats • Non-Modular Format • Used for research grant applications requesting more than $250,000 direct costs per year • Modular Format • Used for research grant applications requesting less than $250,000 direct costs per year

  9. Budget Justification • Specific to the sponsor • Non-Modular and Modular Requirements are different • Provide the justification for each individual in the same order as listed on the budget page (PI first, remaining in role importance) • Present the categories in the same order as on the budget page • Give additional information if it isn’t obvious in the budget

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