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Arbovirus Case Investigation

Arbovirus Case Investigation. Purpose. Determine mode of transmission Characterize the clinical picture of disease Identify risk factors for infection and severe disease Feedback recommendations to patient and family. Part I: Clinical Investigation.

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Arbovirus Case Investigation

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  1. Arbovirus Case Investigation

  2. Purpose • Determine mode of transmission • Characterize the clinical picture of disease • Identify risk factors for infection and severe disease • Feedback recommendations to patient and family

  3. Part I: Clinical Investigation

  4. Possible Exposure/ Transmission Information • Yellow fever vaccination • Transfusion/organ transplant • Given blood • Pregnancy • Breastfeeding • Outdoor activities

  5. Travel History • What are dengue endemic regions? • Why focus on dengue endemic regions? • Determine possible exposure setting • Determine if case is imported

  6. Symptoms • Onset date • Meningitis (CSF white blood cell count >5) • Encephalitis (Evidence of brain involvement) • West Nile Fever • Other (movement disorders, flaccid paralysis, rhabdomyolysis,etc.) • Treatment

  7. Part II: Environmental Investigation

  8. Environment Around the Home • Man-made mosquito breeding sites • Containers • Tires • Tarps • Natural mosquito breeding sites • Ponds • Wooded areas (Hardwoods)

  9. Recommendations • Personal protection • Get rid of tires and containers • Drain birdbaths and pots weekly • Clean gutters • Fill Ditches • Use Larvacidal “dunks”

  10. Latitude and Longitude • Exact location of case • Determine if there is clustering in neighborhoods • Look for patterns and focus area of transmission • Connects human data with bird and mosquito data

  11. Completing the Case Investigation • Yellow Card • Attach all lab results • Blood and/or CSF arbovirus panel • CSF cell count, protein and glucose • Viral cultures if done • Get blood or CSF sent to OLS for confirmatory testing • Complete clinical and environmental investigation

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