1 / 25

2D-NMR

2D-NMR. COSY , CO rrellation S pectroscop Y. COSY. http://www.chem.queensu.ca/FACILITIES/ NMR/nmr/chem806/Web/homo2_files/frame.htm. COSY, CO rrellation S pectroscop Y. 2D-NMR: COSY. C 5 H 10 O 2 IR: 1730 and 1200 cm -1 , no peaks above 3000 cm -1. COSY: C 5 H 10 O 2.

moana
Télécharger la présentation

2D-NMR

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. 2D-NMR

  2. COSY, COrrellation SpectroscopY

  3. COSY http://www.chem.queensu.ca/FACILITIES/ NMR/nmr/chem806/Web/homo2_files/frame.htm

  4. COSY, COrrellation SpectroscopY

  5. 2D-NMR: COSY C5H10O2 IR: 1730 and 1200 cm-1, no peaks above 3000 cm-1

  6. COSY:C5H10O2

  7. C6H12O2 IR: 1730 and 1200 cm-1, no peaks above 3000 cm-1 2D-NMR: COSY

  8. 2D-NMR: COSY

  9. 2 1 2D-NMR: COSY 1H 2H 3H 3H C4H9Cl

  10. 2D-NMR: COSY C14H20O2 (ester)

  11. 2D-NMR: COSY C14H20O2

  12. Given the COSY on the next page, assign all protons and calculate coupling constants, J23, J24 and J34? (Because of the heterocyclic ring, H-2 has the highest chemical shift and the ortho coupling constant J2-3 ~ 4Hz, significantly smaller than a normal ortho coupling constant. 2D-NMR: COSY

  13. 2D-NMR: COSY

  14. Problem - Identify where the methyl is located on the quinoline Ring and assign all protons. Show correlation lines on the COSY spectrum to support your assignments. 2D-NMR: COSY

  15. 2D-NMR 1H-13C Correllation Spectroscopy (HETCOR, HMQC, HSQC)

  16. 2D-NMR 1H-13C Correllation Spectroscopy (HETCOR, HMQC, HSQC) C5H10O

  17. C4H9I

  18. COSY C4H9I HMQC

  19. Unknown: C10H12O

  20. Unknown: C10H12O

  21. Unknown: C10H12O

  22. Unknown: C10H12O

More Related