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Lipid Profiles in SEAL Physicals: A Study on Cholesterol and LDL Standards

This study, conducted by Jim Mucciarone in July 2008, analyzes lipid profiles from 85 SEAL physicals performed in 2007, focusing on age, height, weight, total cholesterol, LDL, HDL, and triglycerides. Results indicate an average age of 32.83 years, with average total cholesterol at 186.6 mg/dl and LDL at 119.9 mg/dl. A significant portion of participants exceeded recommended cholesterol (25.9%) and LDL (27.1%) targets. The study highlights increased mortality risk associated with elevated cholesterol in younger men and emphasizes lifestyle changes as a primary intervention.

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Lipid Profiles in SEAL Physicals: A Study on Cholesterol and LDL Standards

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  1. Lipid Profiles &NSW LCDR Jim Mucciarone NSWG-2 16 July 2008

  2. Study • Reviewed age, height, weight, total cholesterol, LDL, HDL and Triglycerides in 85 SEAL physicals conducted in CY 2007. • Compared results with ATP-III standards for Cholesterol and LDL. • Target for cholesterol < 200 mg/dl • Target for LDL < 130 mg/dl

  3. Results • Avg Age: 32.83 (21-52) • Avg Cholesterol: 186.6 (108-312) • Avg LDL: 119.9 (70-221) • 22/85 (25.9%) Total Chol > 200 • 23/85 (27.1%) LDL > 130

  4. Biases • Age • 5 years AD, Retirement Physicals included • Medications • Excluded personnel known to be on meds • Fasting • Assumed patients fasted appropriately

  5. Significance • Increased serum cholesterol significantly associated with increased risk of death before age 50 (Klag, et al, NEJM, 1993) • Men < 39 y/o with serum cholesterol > 200 have increased overall mortality • > 240 = 2.10 to 3.63 RR of CHD or CVD death • Men < 39 y/o with chol < 200 = 3.8 to 8.7 years of life (Stamler, et al, JAMA, 2000) • “Grow the Force”

  6. Treatment • Therapeutic Lifestyle Changes • Reduce Sat Fats/Cholesterol • Reduce Body Weight • Increase stanols/sterols and fiber • Increase physical activity • Prefer to avoid statins • Lifelong medication • Assoc with muscle pain

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