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Data Blitz 05-26-2009 JYL

Data Blitz 05-26-2009 JYL. [1] Functionalized PPy (Films & Fibers) for the Conjugation of Bioactivemolecules. Types of biomolecules : HA, PEG, LMN, FN, NGF Quantification of conjugated molecules: radio labeling, indirect ELISA, FL. ‘amines’ on PPy surfaces. EDC/NHS or Schiff Base

myles-barrett
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Data Blitz 05-26-2009 JYL

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  1. Data Blitz 05-26-2009 JYL

  2. [1] Functionalized PPy (Films & Fibers) for the Conjugation of Bioactivemolecules • Types of biomolecules : HA, PEG, LMN, FN, NGF • Quantification of conjugated molecules: radio labeling, indirect ELISA, FL ‘amines’ on PPy surfaces EDC/NHS or Schiff Base + what ? • Resistant to cell adhesion • Promotion of cellular activities • (Further cell attachment) EDC/NHS + LMN or FN • Synergies with E-stimulation • Reaction was qualitatively confirmed • Need to improve reaction • Set up quantification matters ‘carboxylates’ on surfaces

  3. [2] Characterization of HA-PPY Gels • Electrochemical properties: LOOKING FOR available and suitable methods NOW • Possible anti-oxidant activities: may complement life-time of HA gels in vivo • EIS • CV • NIR : -OH*(hydroxide radicals) degrades HA mainly in multiple injured tissues : expectation of prolonged residence of HA-PPY gels compared to HA gels

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