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glutamate PowerPoint Presentation

glutamate

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glutamate

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  1. NR1 NR2 allosteric modulators site 1 site 2 ? N-terminal domains (NTDs) Zn2+ (NR2A>>NR2B) ifenprodil (NR2B) site 3 ? agonist -binding domains (ABDs) competitive agonists and antagonists glycine (or D-serine) glutamate site 4 ? pore blockers pore domains 4 1 3 3 1 4 2 2 C-terminal domains