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Understanding Ulcerative Colitis: Epidemiology, Causes, Symptoms, and Treatments

Ulcerative colitis (UC) affects approximately 10-12 per 100,000 people, with peak incidences between 15-25 and 55-65 years old, predominantly seen in the USA, UK, Canada, and Scandinavia. It impacts around 1% of the Swedish population. Factors contributing to UC include genetic predispositions, autoimmune responses, and environmental triggers like smoking and NSAIDs. Symptoms often involve abdominal pain and blood in stools. Treatment options range from medications to various surgical procedures, including proctocolectomy and ileostomies, aimed at managing relapses and maintaining remission.

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Understanding Ulcerative Colitis: Epidemiology, Causes, Symptoms, and Treatments

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  1. Ulverative Colitis

  2. Epidemiology • 10-12 per 100000 • 15-25, 55-65 • USA, UK, Canada, Scandinavia • 1% of Swedish population

  3. Cause • Immune and Autoimmune • Genetic • Smoking, Appendectomy • Lactose, NSAIDS

  4. Signs and symptoms • Abdominal Pain • Perianal disease • Mucus and/or blood with each bowelmovement • Weightloss

  5. Relapses and remissions

  6. remission • A normal life.

  7. relapse • Mild. <4 • Moderate. 4 • Servere. >5

  8. algorythm for Uc • <8, 16%, 30 days • >8, 72%, 30 days

  9. Treatment • Drugs • Alternative medicine • Surgery

  10. Surgical management • Proctocolectomy • Colectomy

  11. Proctocolectomy • Traditional Ileostomy(Brooke) • Continent Ileostomy (Kock)

  12. Colectomy • Ileal pouch-anal anastomosis (IPAA) • Ileorectal anatsomosis (IRA)

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