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Acid Base Balance in Respiration

Acid Base Balance in Respiration. Prof. K. Sivapalan. Acids and Bases in Body. Metabolic- carbon dioxide, lactic acid, ketone bodies Dietary- sodium and potassium salts of weak acids in fruits are metabolised and sodium or potassium bicarbonate remains- alkalies .

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Acid Base Balance in Respiration

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  1. Acid Base Balance in Respiration Prof. K. Sivapalan

  2. Acids and Bases in Body • Metabolic- carbon dioxide, lactic acid, ketone bodies • Dietary- sodium and potassium salts of weak acids in fruits are metabolised and sodium or potassium bicarbonate remains- alkalies. • Removal- by lungs – carbon dioxide • Removal by kidney- hydrogen or bicarbonate. • GIT- vomiting and diarrhoea Respiratory Acid Base Balance

  3. Bufers in Blood • Bicarbonate • Haemoglobin, oxy-haemoglibin [weak] • plasmaproteins Respiratory Acid Base Balance

  4. Acidosis and Alkalosis • Normal pH- 7.4 ± .05. [viable range- 6.8 – 8.0] • Less- acidosis, more- alkalosis • Respiratory failure- accumulation of carbon dioxide leading to respiratory acidosis. [PCO2, HCO3 increased] • Hyperventilation- respiratory alkalosis. [PCO2, HCO3 decreased] • Metabolic acidosis- respiratory compensation- [PCO2, HCO3 decreased] • Metabolic alkalosis- respiratory compensation- [PCO2, HCO3 increased] • Renal compensation- delayed. Respiratory Acid Base Balance

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