1.44k likes | 1.78k Vues
COAST TO COAST WOUND CARE Wound Care Training Program & MDS 3.0. SPERO THEODOROU, MD Surgical Director. Manhattan Eye, Ear Nose and Throat Hospital New York University Plastic and Reconstructive Surgery. WOUND HEALING. Smith Papyrus 1700 BC Ambroise Pare 1500 AC Joseph Lister
E N D
COAST TO COAST WOUND CARE Wound Care Training Program & MDS 3.0
SPERO THEODOROU, MDSurgical Director Manhattan Eye, Ear Nose and Throat Hospital New York University Plastic and Reconstructive Surgery
WOUNDHEALING • Smith Papyrus 1700 BC • Ambroise Pare 1500 AC • Joseph Lister • Alexis Carrrel
WOUNDHEALING • Inflammatory phase Vasoconstriction Vasodilation Histamine Fibronectin 24-48 hrs
WOUNDHEALING • Fibroblastic Phase (proliferative phase) 2ndday (2-4 weeks) fibrous scaffolding Hyaluronic acid collagen deposition Increase tensile strength
WOUNDHEALING • Maturation Phase (remodeling phase) week #3 collagen organization increase in tensile strength 80% Type I collagen : Type III collagen 4:1 scar maturation
WOUNDHEALINGFACTORS • Oxygen Fibroblast proliferation 30-40 mmHg delivery system faults (DM, atherosclerosis…..) Hyperbaric oxygen
WOUNDHEALING • SKIN High tolerance for ischemia Does not operate @ 37 C Great blood supply thermoregulation
WOUNDHEALINGFACTORS • Hematocrit Quality of oxygen delivery Anemia
WOUNDHEALINGFACTORS • Steroids Inhibition of wound macrophages Interference with : fibrogenesis angiogenesis wound contraction
WOUNDHEALINGFACTORS • Vitamin A 25.000 IU 200.000 IU topical ointment Fights steroids collagen deposition stimulation increase breaking strength
WOUNDHEALINGFACTORS • Vitamin C deficiency defective cappilaries local hemorrhages immature fibroblast proliferation no supra normal healing with excess!
WOUNDHEALINGFACTORS • Vitamin E membrane stabilizing properties inhibition of wound healing in large doses antioxidant increase in tensile strength pre radiation therapy
WOUNDHEALINGFACTORS • NSAIDS ASA, Ibuprofen….45% decrease in wound healing at therapeutic doses dose dependant
WOUNDHEALINGFACTORS • Smoking Nicotine……vasoconstriction cappillary flow decrease carboxyhemoglobin hypoxia
WOUNDHEALINGFACTORS • AGE FINALLY! tensile strength wound closure rates phases last longer qualitative changes decrease ischemia tolerance
WOUNDHEALING • NUTRITION serum protein levels 2% prolonged inflammatory phase impaired fibroplasia methionine amino acid
WOUNDHEALINGFACTORS • Hydration • Temperature • Denervation • Chemotherapy • Radiation • Diabetes Mellitus
Diabetes + Wounds • Highest amputation rate • 20% of hospitalizations foot infections • 50% of all non-traumatic amputations • 25% of diabetics severe foot problems during lifetime
Diabetesclinicalpresentation • Small punctuate wound plantar surface beneath a deformed metatarsal head • Neuropathy • Clawing • Microvascular disease • microemboli
Diabetes • Invasion inside the foot along fascial planes • Transmetatarsal amputation • BKA • AKA
Diabetesfactors • Atherosclerosis microvascular macrovascular palpable pulse due to calcification
Diabetesfactors • Uremia • Neuropathy • Sensory deficit • Motor deficit loss of foot arch…2nd metatarsal head MC • Loss of sympathetic activity…no foot sweating….cracking of skin….infection
Diabetesfactors • Hyperglycemia….bacterial nutrients • ? Loss of growth factors • Impaired immune system
Diabetestreatment • Predictors (Margolis et al) • small ulcer size • Shorter duration of time present • Non-caucasian
Diabetestreatment • Control hyperglycemia • Preventive foot maintenance • Care with toenail cutting • Good-fitting footware • Vascular examination (AB index) • doppler
Diabetestreatment • Pressure elimination “off loading” total contact casts 89% removable cast walker 65% half shoes 58.3% Armstrong et al
DiabetesTreatment • Debridment of devitalized tissue • Clindamycin + ciprofloxacin 95% 95% response rate 55% cured 21% improved 21% failure rate
Diabetestreatment • Limit antibiotic ointments • discourage routine Cx • Infection vs colonization • odor
DiabetesTreatment • Hyperbaric Oxygen? • Growth factors Regranex Human Platelet derived GF Frequent debridment
VENOUSSTASISULCERS PATIENT ASSESMENT WEEKS 1-2 H&P Wound evaluation Vascular assessment Infection assessment
VENOUSSTASISULCER • WEEKS 3-8 Ongoing treatment Venous arterial insufficiency Wound care treatment wound excision weekly surgical debridment compression Rx, Elevation
VENOUSSTASISULCER • WEEKS 8 and OVER Skin Coverage grafts flaps Successful healing
PRESSURESORES • Egyptian Mummies 1961 • Decumbre “to lie down” Decubitus sacrum, trochanter,heel,occiput,back • All types of tissue loss from pressure • Ischial tuberosities
PRESSURESORES • EPIDEMIOLOGY General acute care setting 10-18% Long term care facilities 2,3%-28% Home Care setting 0-29%
PRESSURESORES • Incidence Elderly with femoral neck fractures 66% Quadriplegic patients 60%
PRESSURESORES • Pressures sores on admission to LTF 25-33% of residents • After admission 35% • first year 13.2% • second year 21.6%
PRESSURESORES • Residents already in LTF with no PS first year 9.5% second year 20.4%
PRESSURESORES • Mortality Hospital 1yr mortality after PS 59.5% (Thomas et al) LTF 55.7% death within 6weeks (Kennedy et al)
PRESSURESORES • WHAT DOES THIS MEAN? PS not independent risk factor for mortality Indirect marker for coexisting illness, malnutrition,associated comorbidities
PRESSURESORES • Spinal cord injury patients 7-8% direct cause of death Osteomyelitis, sepsis SUPERMAN
PRESSURESORES • COSTS 2004-2005 National Pressure Advisory Panel
PRESSURESORES • COSTS $15,229 per year per patient length of stay increased by 8.2 days
PRESSURESORES • Anatomic distribution Ischial tuberosity 28% Sacrum 36% Heel 30%
PRESSURESORES • Pathophysiology • Neuropathic theory • cappillary pressure 30mmHg • shear