Team Members Cara Dunn Farshad Fahimi Sujan Bhaheetharan Nipun Yamdagni

1. Advisor Client William L. Murphy Timothy Juergens, M.D. Assistant Professor, Department of Biomedical Engineering UW/VA Hospitals – Geriatric psychiatrist/Sleep specialist Medication Adherence Team Members Cara Dunn Farshad Fahimi Sujan Bhaheetharan Nipun Yamdagni

2. Problem Statement • Construct a device with the ability to record time & date information during daily operation of a patient’s standard medication box. • Stationary alarm should be attached in order to alert the user to take medication. • Information should be easily accessed on a computer for the client and patient to discuss, in efforts to ensure proper adherence.

3. Client Requirements • Device must obtain data regarding patient’s adherence of their medications. • Lightweight and durable. • An alarm should alert patient • Total prototype cost may not exceed $300. • Normal use, includes cleaning the device, may not interfere with recording. • Must consume low amounts of power.

4. Motivation & Significance • Compliance: Taking correct amount of the prescribed medicine at the correct time. • Medicine is only helpful when taken correctly. • Only 24% of people take their medicines correctly. • Non-compliance causes 125,000 deaths per year in the USA.

5. Last Semester’s Design • Texas Instruments MSP430 microcontroller with development kit • Program in C language • Recognized open compartments • Used a 7x4 pill box • Switches activated by compartment • Lids • Activation recorded by the microcontroller • Switch matrix utilized

6. Design Limitations • Only had 2x2 switch matrix • Switches were not always activated • No time-keeping method • Lack of sleep function • Parallel port interface • No computer software for interface with pillbox • Cost • The MSP430 microcontroller is too expensive for our need

7. Overview of Current Design • Altered existing parts • Switches • 7x4 Pill Box • Adding new functionality • Power saving functionality • Accurate time keeping • USB Interface • Smaller than previous design • Computer interface

8. Solution to Switch Problem • Altered individual lids • Plexiglas makes flat surface for switch actuation • Higher accuracy • More information from Sujan

9. New Microcontroller • MicroChip’s PIC 18F4550 • Cheaper • More widely known • Allows the use of the B.A.S.I.C. programming language • Easier to interface with: • Clock • USB

10. Electronic Components DLP-USB232M • USB to Serial (TTL) converter • Allows communication between microcontroller and almost any computer • Watch chip • Allows the microcontroller to keep accurate time • Gives non-volatile storage memory DS1307

11. Alarm • Auditory, visual, and vibratory alarm possible • Further investigation required to determine which alarm techniques will be used. • Alarm times are variable

12. Computer Interface • Allows the setting alarm schedule • Allows download of patient data • Easy to use and navigate

13. Present Accomplishments • Established communication between microcontroller and PC • Installed Plexiglas to increase stable contact area between the compartment lid and switch • Began writing code in B.A.S.I.C.

14. Future Work • Convert code from C programming language to B.A.S.I.C. • Implementing time functionality • Integrate alarm clock • Test entire prototype • Have final circuit printed

15. Questions References • VIASYS Healthcare, Inc. • University of Wisconsin – Madison Medical Electronics Lab • http://www.dipdesign.com/usb/usb232.html • http://www.sparkfun.com • http://www.microchip.com