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PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model. SANOFI AT A GLANCE. We are a global healthcare company engaged in the research, development, manufacturing and marketing of healthcare solutions. €33 bn * In sales in 2013. OUR GROUP. R&D

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PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCH Towards a more inclusive model

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  1. PUTTING THE PATIENT AT THE CENTER OF HEALTHCARE RESEARCHTowards a more inclusive model

  2. SANOFI AT A GLANCE • We are a global healthcare company engaged in the research, development, manufacturing and marketing of healthcare solutions. €33 bn* In sales in 2013 OUR GROUP R&D A major biopharmacy player * €32,951 M • 45%of revenues generated by biologics • 80%of development projects are biologics present in more than 100 countries A comprehensive offer of pharmaceuticals, vaccines and innovative therapeutic solutions 112 Industrial sites in 41 countries more than 110 000 employees Information of December 31st 2013 CONFERENCE OF MONTREAL 2014

  3. Sanofi R&D ACCELERATE INNOVATION FOR PATIENTS We act as one to discover and develop therapies that prevent, treat and cure disease. Our main areas of research include: 49 Multiple Sclerosis Diabetes Oncology Rare Diseases Cardio-MetabolicDiseases Immunology Vaccines Animal Health projects and vaccines in clinical development* 9 high potential projects in late stage development* *Information provided as of February 6th, 2014 CONFERENCE OF MONTREAL 2014

  4. The classicINNOVATION model The newINNOVATION model • OUR responsibility • Belief that advances in basic sciences can be easily translated to human disease • A linear process from discovery to development to market with little interactions throughout the innovation cycle • Focus on novel (but not necessarily validated) targets in humans • A strategy of “Many Shots on Goal” Change The R&D Innovation model • Anon-linear process that takes into account provider, purchaser and user metrics including pipeline activity, clinical success, regulatory approval, patient access, satisfaction of unmet need and overall value to society • A greater understanding of human disease • Open innovation and partnership Raising the batting average! CONFERENCE OF MONTREAL 2014

  5. OurPRESIDENT OF R&D PATIENTS ARE THE MISSING LINK CONFERENCE OF MONTREAL 2014

  6. Increasing public awareness & improving clinical trial education • SO WHAT ARE WE DOING ABOUT IT? MAKING CLINICAL TRIALS PATIENT FRIENDLY What do patients know about clinical research? How do they get their facts? How do they know if a study exists? Do they ever hear the results? Bringing patients within the project team e.g. Diabetes Patient Advisors input into study designs, innovation & outreach strategies Innovating to ease patient experience e-informed consent e-technology (e.g. telemetry) Point of care technologies (e.g. Dried Blood Spots) CONFERENCE OF MONTREAL 2014

  7. Opportunities exists from target to use • So what are we doing about it? Before and Beyond clinical trials Target identification Path to proof of concept Effective value Access Partner in Patient Health (PiPH) initiative EU-NA PiPH Council Collaborate | Innovate Challenge Newly created position of Chief Patient Officer CONFERENCE OF MONTREAL 2014

  8. OUR “RAISON D’ETRE” ACCELERATE INNOVATION FOR PATIENTS CONFERENCE OF MONTREAL 2014

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