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CRITICAL PERIOD

CRITICAL PERIOD. Modified from MacLusky and Naftolin Science 1981; 211:1294 - 1303. OH. Testosterone. O. Aromatase. 5 a - Reductase. OH. HO. O. Estradiol. 5 a - DHT. Androgen-dependent sexual dimorphism in the CNS. Ultrastructural differences Neuronal nuclear and nucleolar size

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CRITICAL PERIOD

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  1. CRITICAL PERIOD Modified from MacLusky and Naftolin Science 1981; 211:1294 - 1303

  2. OH Testosterone O Aromatase 5a - Reductase OH HO O Estradiol 5a - DHT

  3. Androgen-dependent sexual dimorphism in the CNS • Ultrastructural differences • Neuronal nuclear and nucleolar size • Differences in synaptic or dendritic organization • Differences in the gross volume of defined cell groups

  4. Arnold and Gorski 1984

  5. Arnold and Gorski 1984

  6. CELL MIGRATION A B Arnold and Gorski 1984

  7. 10 20 30 12 36 60 Age (weeks) Time (hr)

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