1 / 9

Diagnostic Algorithm for Jaundice-Related Pancreatic Conditions: Ultrasound and Tumor Markers

This document outlines a comprehensive work-up algorithm for patients with jaundice, focusing on critical ultrasound findings such as intrahepatic and extrahepatic duct dilatation, along with potential pancreatic tumors. It discusses the significance of tumor markers like CA 19-9 and CEA in diagnosing pancreatic carcinoma. CA 19-9 is frequently elevated in pancreatic cancer and can be a reliable indicator of malignancy, especially at levels above 100 U/mL. In contrast, CEA is less commonly elevated in these patients. Understanding these markers aids in accurate diagnosis and management.

phuong
Télécharger la présentation

Diagnostic Algorithm for Jaundice-Related Pancreatic Conditions: Ultrasound and Tumor Markers

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Laboratory Work-up Unica Francisco

  2. Laboratory Work-Up

  3. Algorithm for patients with jaundice

  4. Ultrasound Findings Pancreatic head Intrahepatic duct dilatation Dilated pancreatic duct Extrahepatic duct dilatation

  5. Tumor Markers

  6. CA 19-9 • CA 19-9 antigen is a sialylated oligosaccharide that is most commonly found on circulating mucins in cancer patients. It can be elevated in acute or chronic biliary disease. • Patients with pancreatic carcinoma, 75-85% have elevated CA 19-9 levels. CA 19-9 value of greater than 100 U/mL is highly specific for malignancy, usually pancreatic.

  7. CEA • Carcinoembryonic antigen (CEA) is a high–molecular weight glycoprotein found normally in fetal tissues. It has commonly been used as a tumor marker in other gastrointestinal malignancies. • The reference range is less than or equal to 2.5 mg/mL. • Only 40-45% of patients with pancreatic carcinoma have elevated CEA levels.

More Related