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Aneurysm Model Prototype: Design Update

This document outlines the design updates and testing of a prototype aneurysm model developed by Sara Goldgraben, Bill Hauser, and Michael Savarese, advised by Dr. Strey, for customer Dr. Chen in BME 441 class. It includes background information, modifications, testing results, and plans for future experiments. Key features such as material selection, flow dynamics, and enhancements in design are discussed, focusing on durability, reusability, and versatility. This prototype aims to advance research and understanding of aneurysm behavior in a controlled setting.

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Aneurysm Model Prototype: Design Update

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  1. Aneurysm Model Prototype: Design Update Sara Goldgraben Bill Hauser Michael Savarese Advisor: Dr. Strey Customer: Dr. Chen BME 441 Design April 3, 2006

  2. Overview • Background • Original Design • Pre-manufacturing Modifications • Initial Prototype Testing • Post-Manufacturing Modifications • Additional Models • Near Future Experiments • Lab Setup

  3. Background • Required parameters • Aneurysm neck: 4mm • Vasculature diameter: 4mm • Aneurysm diameter: 7mm • Flow Velocity: 100cm/min • Transparent Housing • Optical data acquisition • Mechanically strong • Easily Disassembled • Maintenance • Weight measurement of polymer • Durable • Water-tight seals • Seal of aneurysm and input/output flow • Versatilityof Design • Reusability • Variable flow • Velocity • Steady/Pulsatile

  4. Original CAD Design • Size of materials • Plexiglas • O-rings

  5. Pre-Manufacturing Modifications • New Design • Size: 5in x 2in • Straight Fluid Flow • Mostly Seamless • Solid Machined Fittings • Improvements Over Original Design • Smaller Overall Dimensions • Eliminates long entry length • Less Material Used • Less Chance of Leaks • Solid Machined Fittings • Consultation with George Luhrs • Sizes are in closest American standard to our metric requirements • Overall Model Stems From 2D Model Idea • Double Plug • Single Plug • Added Handle with grip • O-ring Sealed Plug • High Tolerance Machined Plug

  6. Initial Prototype Testing • Prototype: High Tolerance Fitting • Results • Positive • Water-tight • Machined Barbed Fittings Work Well • Negative • Aneurysm Cracks • Opaque Tint • Requires Further Polishing

  7. Post-Manufacturing Modifications • Enlarged Plug • Larger Aneurysm Wall • Will reduce aneurysm weakness • Reduction of Opacity • Polishing • Mechanical • Cloth Tip • Wooden Tip (Plausibility not yet known) • Polishing Solution • Heat Based • Baking • Heated Ball Bearings

  8. Additional Models • Lateral Wall Aneurysm Models • 11mm and 13mm Aneurysm • 4mm vessel • Bifurcated Aneurysm • 10-11mm Aneurysm • 4mm vessel

  9. Near Future Experiments • Test Polishing Methods • Test Model with Polymer • Easily Cleaned • Sufficiently Transparent • No Optical Artifacts

  10. Lab Setup • Assembly • Safety Precautions • Barometer set up • Experimental setups • Static flow (reservoir is gravity driven) • Dynamic flow (pump) • Closed loop • Open loop

  11. Conclusion • Budget Breakdown • Pump = $400 • Plexiglas = $80 • Large O-Rings (Not being used) = $35 • Stand/Clamps/etc = $120 • Total so far = $635

  12. Acknowledgements • Professor Chen – Customer • Professor Strey – Advisor • George Luhrs – machined our product • Lester Orlick – Instructional Support Technician CEAS • Greg Pollard – APT Instruments

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