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Chromosomal Basis of Inheritance

Chromosomal Basis of Inheritance. Tracing Heredity through Inheritance of Specific Chromosomes. Sex Determination. Sex Chromosomes : homologous chromosomes that differ in size and genetic composition between males and females. Sex Determination.

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Chromosomal Basis of Inheritance

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  1. Chromosomal Basis of Inheritance Tracing Heredity through Inheritanceof Specific Chromosomes

  2. Sex Determination Sex Chromosomes: homologous chromosomes that differ in size and genetic composition between males and females

  3. Sex Determination Autosome: any chromosome that is not a sex chromosome Humans have 22 pairs of autosomesand 1 pair of sex chromosomes

  4. Human Karyotype showing homologous chromosome pairs

  5. Sex Determination Female Male XX x XY Phenotypic Ratio of Offspring

  6. X-linked Genes Hemophilic Male Non-hemophilic Female (father is hemophilic) Phenotypic Ratio of Offspring

  7. Terms Specific toSex-linked Genes

  8. Patterns of Inheritance • Autosomal Dominant • Autosomal Recessive • X-linked Dominant • X-linked Recessive • Y-Linked Inheritance

  9. Pedigree for Huntington’s Disease, an Autosomal Dominant Trait

  10. Pedigree for Albinism, an Autosomal Recessive Trait

  11. Pedigree for Colorblindness, an X-linked Recessive Trait

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