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  1. Enzyme • Production decreases in the absence of live food or disease, stress, aging, and petrochemicals. Inhibitors of enzyme production: aspirin, Tylenol, Ibuprofen, antibiotics, cleaning solvents, household cleaners, microwave radiation, and heat over 120 degrees.

  2. Our magnificent bodies create over 3,000 different kinds of enzymes, all with their own job descriptions. • Within the cells of our lungs, livers, brain, and digestive system, we should have millions of enzymes when we are healthy.

  3. When our enzyme reserves start to diminish, we become bi-polar, catch a cold or the flu, get arthritis, have allergies, autism, Parkinson’s, inflammation, cancer, digestive problems, heart disease, hormone deficiencies, strokes, and even headache.

  4. Enzymes are proteins produced by living organisms. • They contain amino acids. • Why are these proteins act differently in the body? • Enzymes are catalysts that create many essential biochemical reactions. These enzymes are not consumed or altered in the daily process of the body. • They facilitate chemical reactions in the body very quickly. • Without enzymes some metabolic process would happen very slowly or not at all.

  5. There are 3 kinds of Enzymes • Digestive enzymes • Food enzymes • Metabolic enzymes • The same variety of amino acids that occur in all living things make up enzymes

  6. Why are they important? • What do they do? • What are enzymes?

  7. When enzymes are disrupted, they lose their ability to function. Each enzymes has a specific blueprint and specific function.

  8. Every daily biochemical function in the body requires enzymes to: • Facilitate the building of compounds from the body’s raw materials • Transport elements throughout the body • Break down substances such as food • Eliminate toxins and chemical waste in the body

  9. Enzymes are natural chemical compounds that orchestrate other chemical functions. • Foods are made of chemical elements that require enzymes to break them down and prepare them to be used by the body. • Enzymes deliver nutrients to the body in order to make use of those food elements.

  10. Enzymes need minerals and vitamins to function. • Enzymes free minerals, vitamins, proteins, and hormones to engage in body functions.

  11. Enzymes play a major role in every metabolic process in the body from glandular function and support to hormone production and toxic waste disposal. • Enzymes facilitate digestion and assimilation. • There are enzymes in all food products. Carrots are very high in natural enzymes.

  12. Supplemental enzymes come from plant, microbial, and animal sources. • Plant and microbial sources have a wider range from 2 – 12 pH, although not every enzyme has equal potential in all ranges in all people. • Food enzymes start in the mouth, which is alkaline, continue to the upper stomach. • The upper stomach is alkaline, with a pH of 6.5 – 7, and the food remains there for one hour, then enters the lower stomach, which is acidic, with a pH of 2.5 – 5.

  13. Enzymes are affected by pH differential throughout the different phases of digestion. • Plant enzymes work in the higher pH of the upper stomach and continue to be active throughout the acid of the lower stomach. They then pass into the small intestine, which is alkaline, after which they reactivate and continue working. Research by Beazall 1941, Graham 1977, Griffin 1989.

  14. Plant enzymes have a wider range of activity because they contain more enzymes, such as the following – protease, peptidase, lipase, amylase, glucoamylase, alpha-galactosidase, cellulase, hemicellulase, invertase, malt diastase, lactase, pectinase and phytase.

  15. These enzymes are specific in their action as they breakdown. • They catalyze the breakdown of the protein shell of cancer cells.

  16. After digestion is completed - • Enzymes will break down. • They will pass into the blood stream as amino acids. • They become building blocks in the body. • Protease, amylase, and other enzymes will enter the bloodstream to clean out foreign materials such as free radicals and potential allergens, which create gluten intolerance and other allergies. • Enzymes then make their way back to the liver and pancreas and are used again.

  17. Enzymes are so valuable that the FDA has approved enzyme therapies for treating - • Cancer • Cardiovascular disease • Removal of necrotic (dead) tissue • Gastrointestinal conditions • Pancreatic conditions • Removal of toxic substance from blood

  18. What can enzymes do? • Clean clogged arteries of plaque. • Empty stomach of undigested fat. • Prevent stroke and heart attack. • Enzymes eliminate old fat and proteins left deposited for years, causing cardiovascular problems (Taussig and Nepier 1979). • Protease reduces inflammation processes and enhances circulation and the immune system by improving and increasing the surface area of the red blood cell, allowing it to transport more oxygen (1978 Gulfreurdd, Taussig-Morris).

  19. What can enzymes do? • Enzymes are effective in weight regulation; overweight people are lacking in lipase. • Enzymes prevent allergies and degeneration such as: • Gluten and lactose intolerance • Leaky gut, acid reflux, and heart burn • Environmental allergens • Colds, coughs, flu, and degenerative disease

  20. The story with amylase and the beginning of allergies

  21. Cleaning the colon and the liver • Enzyme help clear the body of undigested proteins and meat. • Undigested starches, sugars, and carbohydrates will ferment fats, turning them rancid. • Toxins create a host for disease such as candida, leaky gut, brian fog, fatigue, hypoglycemia, depression, allergies, and fibromyalgia.

  22. Is a gluten-free or lactose-free diet the answer? • Should I eliminate all yeast products? • When I use oils, I get a rash. Why?

  23. What are some symptoms of autism, Alzheimer’s, Parkinson’s, rheumatoid arthritis, chemical sensitivites? Symptoms include hyperactivity, red face and ear, aggression, headache, head banging, difficulty in sleeping, and yeast overgrowth.

  24. These conditions have been blamed on high phenol foods, food dyes, apples, peanuts, bananas, oranges, cocoa, red grapes, colored fruits, and milk.

  25. Common food additives and PST enzyme substrate, 17 alpha ethenylastrodiol, dopamine, sulfotransferase, catechinoctylgallate, tartrazine, yellow #5, and vanillin are potent inhibitors of human liver enzymes. Vanillin; erythrosin B; actylgallate, an anti-oxidant used in margarine, all inhibit 50% of EE2 substrate activity in the liver.

  26. Sulphate catalyzed by phenol sulfotransferase (PST enzyme) is very important in preventing removal of catecholamines • PST enzymes are important for detoxification of xenobiotics. • High concentration of sulfotransferase in the reservoir areas of the left and right colon indicate the importance of detoxification by sulfation and also in activating mutagen in the same area. • Diets high in fats can often alter PST activity. • Omega 3, 6, 9 increase allergic reactions, causing asthma attacks.

  27. Autism in gastrointestinal symptoms • Autistic children show high GI inflammation and dysfunction in both upper and lower GI tracts. • Decreased enzyme activities were reported in children with autism (Horrath K. PermannJa. Current, Gastroenterology Report 2002) • Treatment of digestive problems with enzymes had a positive effect on autistic behavior.

  28. Candy flavoring is a source of salicylate poisoning. Aspirin metabolite causes focal hemorrhaging and cell death in rats. Xenoestrogen in diet and environment causes endocrine disruption.

  29. Phenolic sensitivity from the inhibition of the PST pathway can be caused by food additives, flavorings, colorants, and phenolic medications, such as steroidal anti-inflammatory drugs.

  30. Phenolics all cause the inability to metabolize sulfur compounds in humans. People low in PST or low sulfate have problems handling environmental chemicals, some phenolic medications, or even their own body chemicals. These people are those with Parkinson’s, Autism, Alzheimer’s, Rheumatoid arthritis, chemical sensitivity, intolerance to oils, and gluten.

  31. Phenols are a necessary part of life. All foods contain some phenolic compounds, especially fruits and vegetables. Food additives, colorants, dyes, flavorings, BH, BHT, and TBHQ all block the PST enzyme and pancreatic enzymes.

  32. Autism children have a deficiency in a key detoxification pathway according to Dr. Rosemary Waering’s research. According to research by O’Reilly and Waering, autistic children are very low in organic sulfur (i.e. MSM), as much as 15%.

  33. A report from McFadden in 1996 stated that a large number of adults cannot metabolize sulfur. These same people have had trouble handling environmental chemicals and become overly sensitive to medications. We see this with Parkinson’s, Alzheimer’s, rheumatoid arthritis.

  34. Enzyme deficiencies are a growing problem. For more information on how to take enzymes, review Chapters 9 and 19 in the Essential Oils Desk Reference.

  35. ESSENTIALZYME Enzyme Blend of Animal Origin (Delayed Release Half of Tablet), Pancrealipase, Pancreatin 10X, Trysin, Betaine HCI Enzyme Blend of Vegetable Origin (Immediate Release Half of Tablet), Bromelain 600, Sulfite Free, Thyme Leaf Powder, Carrot Powder, Alfalfa Sprouts, Alfalfa Powder (Leaf), Papain (2000 USP Units/mg), Sulfite Free Cumin Seed Powder Essentialzyme Oil Blend, Anise, Fennel, Peppermint, Tarragon, Clove, Peppermint

  36. Animal Enzyme Blend Pancreatin (NF 10X), Bee Pollen Powder, Lipase, Essential Oil Blend, Fennel, Lemongrass, Ginger, Tarragon, Anise Vegetable Enzyme Blend Amylase (100,000 DU), Cellulase (24,000 CU), Protease 3.0 (30 SAPU), Protease 4.5 (35,000 HUT), Protease 6.0 (25,000 HUT), Lipase (600 FCC LU), Phytase (40 FTU), Bromelain (750,000 FCC PU), Papain (12,000,000 FCC PU, Sulfite-Free), Peptidase (5000HUT), Riboflavin USP, Anise, Ginger, Rosemary, Tarragon, Fennel