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The effect of guarana versus caffeine on fat oxidation in healthy college students

The effect of guarana versus caffeine on fat oxidation in healthy college students. Corrine A., Christine C., Veronica G., Jacqueline J., Lauren M., Emily S., & Tim W. Guarana ( Paullinia Cupana ). Traditionally used as a tonic for : Heat fatigue Migraine Diarrhea Hypertension

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The effect of guarana versus caffeine on fat oxidation in healthy college students

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  1. The effect of guarana versus caffeine on fat oxidation in healthy college students Corrine A., Christine C., Veronica G., Jacqueline J., Lauren M., Emily S., & Tim W.

  2. Guarana (Paullinia Cupana)

  3. Traditionally used as a tonic for: Heat fatigue Migraine Diarrhea Hypertension Currently used as a supplement for: Stamina General stimulant Background

  4. Guaranine / Guarana Caffeine / Coffee Theine / Tea contains 5-10% naturally occurring caffeine guaranine is modified by other components of guarana Guaranine = Caffeine

  5. Guarana • guarana contains : threophylline & theobromine • guarana is rich in seed fiber, tannins and saponins • These compounds are said to be released slowly over 6 hours • Guarana toxic at doses @ 10 grams

  6. Hypothesis • Due to the synergistic effect of guarana’s main constituents, we speculate that an equivalent dose of guaranine will fat oxidation for a longer amount of time than caffeine

  7. Purpose To determine if supplementation with guarana will increase fat oxidation for a greater amount of time than caffeine in healthy inviduals in a resting state.

  8. Methods • Controlled clinical trial • Crossover design • 6 subjects (1 male & 5 females) • Similar breakfast consumed before study • RER measured w/ Metabolic Cart • Baseline RER measured

  9. Methods • 250 mg capsule of guarana (90 mg caffeine) • 200 mg No Doz split in half (~90 mg caffeine) • RER measured every hour for 5 hours • No food or drink (except water) • Mean and standard deviation calculated

  10. Results

  11. Results

  12. Discussion • 4 out of the 6 subjects demonstrated the expected results, although to only a small degree • Insufficient evidence to conclude that guarana encourages fat metabolism for a longer time than caffeine • No difference between guarana & caffeine OR poor study design?

  13. Limitations • Small sample size • Subjects not blinded • Study not long enough • Food as a confounder • dinner the night before • breakfast • fast • Residual caffeine from decaf coffee

  14. Limitations • Purity of guarana capsule • Additives in No Doz • Menstrual cycle as possible confounder • Differences in lean body mass • Habitual caffeine use • Movie induced giggling / stress

  15. Conclusions • A large difference between guarana and caffeine was not observed • A more controlled trial could provide more reliable results • More time required to observe trends

  16. Thank you! Questions???

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