'Dissolution rate' diaporamas de présentation

Dosage Form Design: Pharmaceutical and Formulation Considerations

Dosage Form Design: Pharmaceutical and Formulation Considerations. Asso. Prof. Ma. Cristina C. Doria Faculty of Pharmacy. Dosage Form Design. Pharmaceutics - study on the: formulation, manufacture, stability, and effectiveness of pharmaceutical dosage forms

2.94k views • 103 slides

Solid preparations

Solid preparations. Chapter 4. I.Introduction. A.characteristics (1)better stability when compared with liquid preparations (2)similar preparation process (3)absorbed into blood circulation only after released from preparations. B.Flow profiles of preparation process raw materials

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Recent Developments on Groundwater Modelling

Recent Developments on Groundwater Modelling. Felix qui potuit rerum cognoscere causas. (Virgilio). Jesus Carrera Institute Jaume Almera (IJA) for Earth Sciences Higher Council for Scientific Research (CSIC) Barcelona, Spain. Contents. GW Modelling Where are we now? Where are we heading?

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Pharmaceultical dosage form design and drug delivery systems

Pharmaceultical dosage form design and drug delivery systems. Lecturer Dr Athmar Dhahir Habeeb PhD in industrial pharmacy and pharmaceutical formulations. pH-Solubility Profile. 5. Indomethacin (weak acid). 4. 3. Chlorpromazine (weak base). Log aqueous solubility ( m mol ). 2. 1.

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Dissolution of calcite in sediments -- metabolic dissolution

Dissolution of calcite in sediments -- metabolic dissolution. CaCO3 accumulation in marine sediments. CaCO3 is the predominant biogenic sediment constituent over much of the ocean Changes in the marine alkalinity budget can drive changes in atmospheric PCO2

815 views • 40 slides

Controlled Release Oral Drug Delivery System

Controlled Release Oral Drug Delivery System. Dr. Basavaraj K. Nanjwade M.Pharm., Ph.D Professor of Pharmaceutics Department of Pharmaceutics JN Medical College KEL University, Belgaum- 590010, Karnataka, India E-mail: bknanjwade@yahoo.co.in Cell No: 00919742431000. Contents.

3.17k views • 37 slides

Controlled Release Oral Drug Delivery System

Controlled Release Oral Drug Delivery System. Dr. Basavaraj K. Nanjwade M.Pharm., Ph.D Professor of Pharmaceutics Department of Pharmaceutics JN Medical College KEL University, Belgaum- 590010, Karnataka, India E-mail: bknanjwade@yahoo.co.in Cell No: 00919742431000. Contents.

2.88k views • 37 slides

Peristaltic Crawler for the Removal of Radioactive Plugs

Peristaltic Crawler for the Removal of Radioactive Plugs. Presented by: Lee Brady DOE Fellow. Overview . Problem Statement Motivation Proposed Solution Design Metrics Mechanical Designs Vs. Pneumatic Design Prototype Characterizing Sludge Final Design Fault Tolerant

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Bio-pharmaceutics of Sustained Release Dosage Forms

Bio-pharmaceutics of Sustained Release Dosage Forms. INTRODUCTION. DEFINITIONS:-

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Chapter 6 Solid preparation

Chapter 6 Solid preparation. Dr. Lei Luo 15730075066@sina.cn. Requirements To understand the definition, characteristics and preparation methods of powders, granules, capsules, drops and pills .

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RECENT DEVELOPMENTS IN REACTIVE TRANSPORT

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Lo sviluppo di un farmaco: dal laboratorio al mercato

Lo sviluppo di un farmaco: dal laboratorio al mercato. Fasi dello sviluppo di un farmaco. Drug development Farmacodinamica Farmacocinetica Tossicologia Sviluppo chimico Sviluppo farmaceutico Sviluppo analitico cGLP compliance. Clinical Trials Studi clinici cGCP compliance.

614 views • 29 slides

Impact of the cementitious engineered barriers on the stability of the high-level waste matrices

Impact of the cementitious engineered barriers on the stability of the high-level waste matrices. Karel Lemmens, Christelle Cachoir, Karine Ferrand, Thierry Mennecart, Ben Gielen, Regina Vercauter Euridice Exchange meeting Mol, January 29th 2009.

416 views • 27 slides

Pathway of Absorption

Pathway of Absorption. epithelium. connective tissue, muscle. endothelium. blood. Cell Membrane. Absorption. Affected by drug chemical physical properties dissolution rate (solids) hydrophilicity/hydrophobicity physiological factors route of administration drug distribution.

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The Electrolitolysis ( ELLYS )

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By Chintal Desai

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Polymorphs in Pharmaceutical Products

Polymorphs in Pharmaceutical Products. Christopher Low QAS TC1600 571-272-0951 Christopher.low@uspto.gov. Definition Of Polymorphs. Polymorphs are different crystalline forms of the same pure substance in which molecules have different arrangements and/or different molecular conformation. .

476 views • 18 slides

K. Adrjanowicz , Z. Wojnarowska, P. Wlodarczyk, K. Grzybowska, K. Kaminski, M. Paluch

Molecular dynamics in pharmaceutically important hydrochloride salts studied by Dielectric Spectroscopy. K. Adrjanowicz , Z. Wojnarowska, P. Wlodarczyk, K. Grzybowska, K. Kaminski, M. Paluch Institute of Physics, University of Silelesia , Katowice, Poland.

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Thermal and dissolution studies of Cefpodoxime proxetil drug and tablets

Cefpodoxime proxetil is commonly used antibacterial drug. Thermal analysis and dissolution studies are routinely conducted by pharmaceutical industries in order to evaluate the drug stability, the drugexcipient interaction and compatibility. In this study dynamic thermogravimetry (TG) experiments were performed in flowing dry air atmosphere (20 ml min-1) to investigate the thermal decomposition of cefpodoxime proxetil drug and tablets (A, B and C) containing different excipients. The TG curve of cefpodoxime proxetil drug shows single decomposition process while tablets (A, B and C) display two. Decomposition activation energies and thermal rate constant (kT) were determined using model-free methods viz. Kissinger, Friedman, Flynn-Wall-Ozawa, and modified Coats-Redfern. The dissolution study of samples was carried out in accordance of United State Pharmacopeia (USP 32) and Kitazawa equation was used for kinetics. Samples are found to have following sequence of the thermal stability: tablet B < cefpodoxime proxetil drug < tablet A < tablet C and the dissolution order: tablet B < cefpodoxime proxetil drug < tablet A < tablet C. The thermal rate constant (kT) and dissolution rate constant (kD) were also correlated graphically and found to have very good correlation with regression coefficient close to 1.

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