'Gene 2' diaporamas de présentation

Elements of Bioinformatics (14F001) TP2: Gene prediction 22 October 2012 CORRECTIONS

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Microarray Data Normalization and Analysis

Microarray Data Normalization and Analysis. John Quackenbush 15 February 2003 MGED/AAAS Denver. The Experimental Design. The Experimental Design dictates a good deal of what you can do with the data Good normalization and processing reflects the experimental design

871 views • 64 slides

Gene Networks Inference

Metabolic space. Metabolite 1. Metabolite 2. Protein space. Protein 2. Complex 3-4. Protein 4. Protein 1. Protein 3. Gene 4. Gene 2. Gene 3. Gene 1. Gene space. Gene Networks Inference. Biochemical interaction network. Projection to the gene space. Gene 4. Gene 2.

720 views • 55 slides

Microarray Data Analysis - II

Microarray Data Analysis - II. FIOCRUZ Bioinformatics Workshop 6 June, 2001. Challenges in Microarray Data Analysis. Spot Identification and Quantitation. Normalization of data from each experiment. Identification of Differentially Expressed Genes

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Classifiers!!!

Classifiers!!!. BCH394P/364C Systems Biology / Bioinformatics. Edward Marcotte, Univ of Texas at Austin.

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Review of statistical modeling and probability theory

Review of statistical modeling and probability theory. Alan Moses ML4bio. What is modeling?. Describe some observations in a simple, more compact way. X = (X 1 ,X 2 ). What is modeling?. Describe some observations in a simple, more compact way. G m. Model: a = -. r 2.

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Introduction of Genome Research

Introduction of Genome Research. Bioinformatics Research Center Institute of Biomedical S ciences ACADEMIA SINICA. ???. www.sinica.edu.tw/~trees/bioinformatics E-mail: trees@gate.sinica.edu.tw. Introduction. Outline. Introduction. Some Research Topics. Related Links and Resources.

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Boolean relationship between genes can be estimated from microarray data.

Inference of Boolean Functions. Boolean relationship between genes can be estimated from microarray data. Experiment 1. Experiment 2. Experiment 3. Experiment 4. Experiment 5. Experiment 6. Experiment 1. Experiment 2. Experiment 3. Experiment 4. Experiment 5. Experiment 6. Examples:

517 views • 28 slides

Reconstruction of Gene Regulatory Networks from RNA-Seq Data

Reconstruction of Gene Regulatory Networks from RNA-Seq Data. Jianlin Jack Cheng Computer Science Department University of Missouri, Columbia ACM-BCB, 2014. Big Data Challenge in Genomic Era. Omics Data. Biological Experiments. DNA/RNA Sequencing. Genomics Transcriptomics Proteomics

792 views • 21 slides

EPISTASIS

EPISTASIS. Dr. S. Ramgopal Rao. Epistatic Gene Interactions. Gene interactions occur when two or more different genes influence the outcome of a single trait Most morphological traits (height, weight, color) are affected by multiple genes

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Comparative Genomics in Basidiomycetes - Analyzing multigene families

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Epistasis

Epistasis. Definition. Epistasis is a form of gene interaction in which one pair of alleles (gene) masks the phenotypic expression of another. There are no new phenotypes produced by this type of gene interaction. Epistatic versus Hypostatic.

657 views • 16 slides

Epistasis

Epistasis. Definition. Epistasis is a form of gene interaction in which one gene masks the phenotypic expression of another. There are no new phenotypes produced by this type of gene interaction. Epistatic versus Hypostatic.

483 views • 16 slides

Epistasis

Epistasis. Definition. Epistasis is a form of gene interaction in which one gene masks the phenotypic expression of another. There are no new phenotypes produced by this type of gene interaction. Epistatic versus Hypostatic.

174 views • 16 slides

Phylogenomics Symposium and Software School

Phylogenomics Symposium and Software School. Co-Sponsored by the SSB and NSF grant 0733029. NSF DEB 0733029. Large-Scale Simultaneous Multiple Alignment and Phylogeny Estimation PIs: Tandy Warnow (UT-Austin) Randy Linder (UT-Austin) Mark Holder (Kansas) Jim Leebens -Mack (Georgia)

211 views • 14 slides

Phylogenomics Symposium and Software School

Phylogenomics Symposium and Software School. Co-Sponsored by the SSB and NSF grant 0733029. NSF DEB 0733029. Large-Scale Simultaneous Multiple Alignment and Phylogeny Estimation PIs: Tandy Warnow (UT-Austin) Randy Linder (UT-Austin) Mark Holder (Kansas) Jim Leebens -Mack (Georgia)

143 views • 14 slides

Genes That Direct Transcription Co-activator Proteins : Do they disrupt/alter seed development?

Genes That Direct Transcription Co-activator Proteins : Do they disrupt/alter seed development?. Gene 1: At5g09250 Gene 2: At5g09240 Combiz Richard Abdolrahimi 06-09-2005 HC 70AL Gene Discovery Lab Dr. Bob Goldberg HHMI Institute/UCLA.

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Objectives

Objectives. Evaluate models that illustrate the origin of variation in a population. Last time: What are the sources of genetic variation?. What are the sources of new alleles and new combinations of alleles in a population of snails? Random mutation; Sexual reproduction;

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Grow on 5-FOA

ARS. ARS. Gene 1 knockout. Gene 2 knockout. CEN. CEN. HIS3. HIS3. ARS. ARS. CEN. CEN. ARS. ARS. CEN. CEN. URA3. URA3. Gene 2. Gene 2. Gene 1. Gene 1. LEU2. LEU2. Mutant Gene 1. Mutant Gene 1. Gene 1 knockout. Mutant Gene 2. Mutant Gene 2. Gene 2 knockout.

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Grow on 5-FOA

ARS. ARS. Gene 1 knockout. Gene 2 knockout. CEN. CEN. HIS3. HIS3. ARS. ARS. CEN. CEN. ARS. ARS. CEN. CEN. URA3. URA3. Gene 2. Gene 2. Gene 1. Gene 1. LEU2. LEU2. Mutant Gene 1. Mutant Gene 1. Gene 1 knockout. Mutant Gene 2. Mutant Gene 2. Gene 2 knockout.

43 views • 4 slides