'General transcription factors' diaporamas de présentation

General Transcription Factors

Chapter 11. General Transcription Factors. False-color transmission electron micrograph of RNAs being synthesized on a DNA template, forming a feather-like structure. Table of contents. Class II Factors Class I Factors UBF Class III Factors. 11.1 Class II Factors.

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Fig. 11-CO, p.264

Fig. 11-CO, p.264. Learning Objectives. How Does Transcription Take Place in Prokaryotes? How Is Transcription Regulated in Prokaryotes? How Does Transcription Take Place in Eukaryotes? How Is Transcription Regulated in Eukaryotes? How Is RNA Modified after Transcription?

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Review from last time

Review from last time. Coding and non-coding repeats make up the moderately repetitive portion of the eukaryotic genome Polyploidization and gene duplication contribute to structural and functional genome change Transposable elements contribute to structural and functional genome change

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Control of Gene Expression

Control of Gene Expression. ECB Ch 8. An overview of gene expression. The different cell types of a multicellular organism contain the same DNA Different cell types produce different sets of proteins A cell can change the expression of its genes in response to external signals

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Transcriptional regulation in Eukaryotes

Transcriptional regulation in Eukaryotes. The regulatory elements of bacterial, yeast, and human genes. Regulation of gene expression in Eukaryotes. The gene control region of a typical eucaryotic gene. CONSERVED MECHANISMS OF TRANSCRIPTIONAL REGULATION FROM YEAST TO MAMMALS.

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Controls over Genes

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Transcription

Transcription. May, 2013. The Central Dogma. DNA. Transcription. R NA. Translation. Protein. Transcription. Process in which cells make a copy of their genetic instructions DNA into RNA. Revisiting RNA. Uracil. Steps. Initiation. Elongation. Termination. Modification. Initiation.

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Transcription in Eukaryotes

Transcription in Eukaryotes. Class II promoters:. *Core Promoter TATA box TFIIB Recognition Element (BRE) Initiator (Inr) Downstream Promoter Element (DPE) *Upstream Promoter Element. Transcription Initiation in Eukaryotes. General Transcription Factors and the Pre-initiation complex:.

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Eukaryotic Genome & Gene Regulation

Eukaryotic Genome & Gene Regulation. The entire genome of the eukaryotic organism is present in every cell of the organism. Although all genes are present, the numbers and types that are actively transcribed can be managed through the processing and packaging of the DNA. DNA packing. histones

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