'Insulin receptor' diaporamas de présentation

Pathophysiology of Diabetes

Pathophysiology of Diabetes. Farhad Hosseinpanah Obesity Research Center Research Institute for Endocrine sciences Shahid Beheshti University of medical sciences Jan 11, 2014 Tehran. Agenda. Overview of classification Physiology of insulin Pathophysiology of Type 1

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Bio-ontologies for Annotation and Service Discovery

Bio-ontologies for Annotation and Service Discovery. Chris Wroe ( + material from Carole Goble, Alan Rector, Jeremy Rogers, Ian Horrocks) University of Manchester, UK. Overview. Example driven tour of the why , what and how of ontologies in life sciences

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PANCREATIC HORMONES

PANCREATIC HORMONES. OBJECTIVES. To know the Functional Anatomy of Pancreas To be able to differentiate b/w exocrine & endocrine functions of Pancreas To be able to enlist the hormones produced by the pancreas & the pancreatic cells that produce them

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Endocrine Physiology The Endocrine Pancreas

Endocrine Physiology The Endocrine Pancreas. Dr. Khalid Al-Regaiey. Pancreas. A triangular gland, which has both exocrine and endocrine cells, located behind the stomach Strategic location Acinar cells produce an enzyme-rich juice used for digestion (exocrine product)

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Cellular Signaling Mechanisms Receptor Tyrosine Kinases Cytokine Receptors Nuclear Receptors

Cellular Signaling Mechanisms Receptor Tyrosine Kinases Cytokine Receptors Nuclear Receptors Death Receptors Phar 735/590 Winter 2006 Mark Leid Office: Pharmacy 407 Tel: 737-5809 E mail: Mark.Leid@oregonstate.edu. Objective.

848 views • 48 slides

ALK in lung cancer: Past, present, and future

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The serious search for an anti-aging pill.

The serious search for an anti-aging pill. Mark Lane, Donald Ingram George Roth. Scientists found over 60 years ago that rats fed a calorie restricted (CR) diet lived longer on average than free-feeding rats and had a reduced incidence of conditions that become increasingly common in old age.

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Regulation of Hepatic Glucose Metabolism

Regulation of Hepatic Glucose Metabolism. SEUNG-HOI KOO Sungkyunkwan University, School of Medicine 05-30-2008. Insulin regulates glucose homeostasis. Annu Rev Physiol. 2006;68:123-58. Insulin regulates Foxo activity. Foxo1 regulates hepatic glucose production.

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Control, Coordination and Feedback

Control, Coordination and Feedback. Blood glucose control. What is glucose? Why is glucose in the blood? Where does it come from? Where does it go? What is it there for? How much is there? How do you measure it? When does the concentration increase? When does the concentration decrease?.

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SYSTEMS BIOLOGY APPROACH TO MODEL INFLAMMATION IN HUMAN CELLS

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Figure 16.01 Cellular locations of major metabolic pathways.

Figure 16.01 Cellular locations of major metabolic pathways. Figure 16.02 The Cori cycle. Figure 16.03 The glucose-alanine cycle. Figure 16.04 Elements of a signal transduction pathway. Figure 16.05 Structure of human insulin. Figure 16.06 Pancreatic islet cells.

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Diabetes mellitus und Krebs

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RECEPTOR FAMILIES

RECEPTOR FAMILIES. RECEPTOR FAMILIES. RECEPTOR FAMILIES. By Prof. Omnia Nayel Assoc. Prof. Osama Yousif. ilo s. By the end of this lecture you will be able to : . Classify receptors into their main superfamilies. Recognize their different transduction mechanism.

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528 views • 18 slides

Cellular Uptake of Glucose

Cellular Uptake of Glucose. Cellular Uptake of Glucose. 1.) Gradient usually exists ECF>ICF (HK keeps ICF low). 80-110 mg/dl euglycemia < 45 mg/dl hypoglycemia > 150-200 mg/dl after CHO meal (ie, below T max ) > 300-600 mg/dl uncontrolled diabetes.

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M von Mehren, M Heinrich, S Schuetze, K Ganjoo, J Yu, J Yap, AD Van den Abbeele,

Interim Analysis of SARC022, A Phase II study of Linsitinib in Pediatric and Adult Wild Type (WT) Gastrointestinal Stromal Tumors (GIST). M von Mehren, M Heinrich, S Schuetze, K Ganjoo, J Yu, J Yap, AD Van den Abbeele, J Wright, S George. Background.

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Glucose homeostasis

Glucose homeostasis. Insulin lowers blood glucose (yes, but...) Insulin enables glucose metabolism in cells (yes, but...) Insulin exerts its effect through insulin receptor a transmembrane protein with kinase activity

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Second Messengers

Second Messengers. Glucose Mobilization- cAMP. A second Major signalling Pathway. Glucagon + Epinephrine (Hormone) acts on liver cells ----------- promotes release of glucose to blood stream. Insulin acts on liver and muscle cells to initiate an opposite series of reaction.

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Chap. 16 Problem 1

Chap. 16 Problem 1.

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NPY / AGRP Neuron

Appetite-decreasing Effects of PYY3-36. Pancreas. Colon. Fat Tissue. Stomach. Leptin. Insulin. Ghrelin. PYY3-36. Ghrelin receptor. Insulin receptor. Leptin receptor. Y2R. NPY / AGRP Neuron. POMC Neuron. ?- MSH. AGRP. hypothalamus. NPY. Arcuate nucleus. Y1R. MC4R/ MC3R.

282 views • 1 slides