'Latently infected' diaporamas de présentation

HIV/AIDS: How Mathematics Has Saved Lives

560 views • 47 slides

HIV Virology & Resistance

Themes Viral load Tropism Drug resistance. HIV Virology & Resistance. Anna Maria Geretti Institute of Infection & Global Health. The HIV Virology Timeline. Is HIV eradication possible?. HIV replicates at high levels throughout the infection. HAART. Viral load testing.

677 views • 45 slides

Antiretroviral Drug Resistance

Antiretroviral Drug Resistance. Anna Maria Geretti UCL Medical School & Royal Free Hampstead Medical School, London. Host-related factors Adherence Tolerability Immunity Genetics. Drug-related factors Potency PK properties Genetic barrier. Virus-related factors Viral load

505 views • 33 slides

420 views • 28 slides

372 views • 28 slides

ImmunoPathogenesis of HIV Disease

ImmunoPathogenesis of HIV Disease. Overview of HIV Epidemic Basic biology of HIV-1 Stages of HIV Disease Viral and Cellular Dynamics after HAART HIV Therapy and Future Directions in Pathogenesis Research . Overview of HIV Epidemic. Origin of virus Scope of worldwide Epidemic

613 views • 24 slides

What are the determinants of HIV persistence?

Cell- and Tissue-based Measures of Viral Persistence Are Associated with Immune Activation and PD-1-Expressing CD4+ T cells. H Hatano 1 , V Jain 1 , PW Hunt 1 , JN Martin 1 , TH Lee 2 , E Sinclair 1 , JM McCune 1 , F Hecht 1 , MP Busch 1,2 , SG Deeks 1

360 views • 22 slides

David M. Margolis , MD Professor of Medicine

Towards an HIV cure: m edical, social and ethical challenges in research and testing. David M. Margolis , MD Professor of Medicine. 1997. -. Latent HIV infection persists despite ART: Stable R esting CD4 + Cell I nfection. 10000. Time to eradication > 73.4 years. 1000. 100. 10.

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Differential impact of IL-7 and IL-15 on HIV reservoir persistence

Differential impact of IL-7 and IL-15 on HIV reservoir persistence. Claire Vandergeeten, PhD. IAS, Rome, July 18th 2011. Why are we interested in the study of the role of IL-7 and IL-15 on HIV reservoir persistence?.

293 views • 12 slides

Jurkat Cells +HAART

1. Select for latent infection. 2. Map integration sites. 3. siRNA library in individual clones to ID human regions which affect activation. HIV-1. Massively Parallel Pyro - sequencing. Jurkat Cells +HAART. HAART kills active HIV populations, selecting for latent infections.

150 views • 3 slides

JQ1S

Supplementary Figure 1. JQ1S and JQ1R activity on three latently infected T cell clones (11B10, BA1 and CA5). . Fold Activation. JQ1S.

108 views • 1 slides