'Mrna levels' diaporamas de présentation

Correlating mRNA and protein abundance via genomic and proteomic characteristics

Correlating mRNA and protein abundance via genomic and proteomic characteristics. Dov Greenbaum Gerstein Lab Thesis Seminar April 21, 2004. outline. Why analyze mRNA and protein correlations Background Disparate Data Sources Correlating mRNA and Protein Results Other analyses

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RNA interference (RNAi) Natasha Caplen Gene Silencing Section, Genetics Branch, CCR, NCI

RNA interference (RNAi) Natasha Caplen Gene Silencing Section, Genetics Branch, CCR, NCI. RNAi: Truly a story of translational research.

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Statistical Methods for the Screening and Classification of Microarray Gene Expression Data

Statistical Methods for the Screening and Classification of Microarray Gene Expression Data. Geoff McLachlan Department of Mathematics & Institute for Molecular Bioscience University of Queensland. http://www.maths.uq.edu.au/~gjm.

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Introduction to Affymetrix Microarrays

Introduction to Affymetrix Microarrays. Stem Cell Network Microarray Course, Unit 1 August 2006. Goals. Review technology & terminology of Affymetrix GeneChips Describe some methods for processing raw data from Affymetrix chips and generating expression values.

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Bioinformatics for biomedicine More annotation, Gene Ontology and pathways

Bioinformatics for biomedicine More annotation, Gene Ontology and pathways. Lecture 6, 2006-10-24 Per Kraulis http://biomedicum.ut.ee/~kraulis. What is bioinformatics? Basic databases and tools Sequence searches: BLAST, FASTA Multiple alignments, phylogenetic trees

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Merger of NIH-NIDA & NIH-NIAAA?: Systems Science

Merger of NIH-NIDA & NIH-NIAAA?: Systems Science. Mary Jeanne Kreek, M.D. Patrick E. and Beatrice M. Haggerty Professor Head of Laboratory The Laboratory of the Biology of Addictive Diseases Senior Physician The Rockefeller University September 23, 2009 National Institutes of Health

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The authors have no financial interest in this presentation

Evaluation of Collagen-derived Antiangiogenic factors and Matrix Metalloproteinases in Lens epithelial cells of Pediatric eyes with Persistent Fetal Vasculature (PFV). Shail A. Vasavada, DO Devarshi Gajjar, PhD Kaid Johar SR, PhD Abhay Vasavada, MS, FRCS (England).

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S. Caron, et al. Arterioscler Thromb Vasc Biol 2011;31:513-9

S. Caron, et al. Arterioscler Thromb Vasc Biol 2011;31:513-9. Hepatic apoCIII mRNA is repressed in LIR-KO mice

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Figure 1. Caron S & Huaman Samanez C

Vehicle. Vehicle. Vehicle. Vehicle. Vehicle. WAY362450. CDCA. GW4064. INT-747. GW4064. **. ChREBP-Mlx. HNF4 ?. ChORE. DR-1. -144. -125. -169. L4. L3. (L4L3) region of the L-PK promoter. F. F. RF. RF. RF + INT-747. RF + INT-747. ***. **. *. **. ***. 25. ***. ***.

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DAD1

Plant Cell Reports Wound-Induced Expression of DEFECTIVE IN ANTHER DEHISCENCE1 and DAD1-Like Lipase Genes is Mediated by Both CORONATINE INSENSITIVE1 -Dependent and Independent Pathways in Arabidopsis thaliana

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Supporting Figure 1: Acute leptin and IL-6 treatments on pY-STAT3 phosphorylation in HuH7 cells.

A. Empty vector. LepRb. Empty vector. LepRb. Leptin: - - - + + + - - - + + +. Leptin: - - - + + + - - - + + +. pSTAT3 (Y705). STAT3. 5 minutes of treatment. 15 minutes of treatment. 0.2. 0.18. pcDNA3-Co. 0.16.

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Days

20% O 2. Relative cell number. 1 % O 2. Days. Supplementary Fig. 1. A. B. C. Tumor Volume (mm 3 ). *. Vascular density. 25. 20. D. E. 15. 10. 5. Depth of invasion ( m m). 0. active caspase-3 positive cells / mm 2. Ki-67 positive cells (%). shNT. Parent. shCBS#07.

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LEPTIN

RESISTIN. VISFATIN. LEPTIN. ADIPONECTIN. RA. OA. SLE. ARTICULAR ACTIVITIES. CHEMERIN. LIPOCALIN 2. SAA3.

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PPP1R11

8. (a). 7. PPP1R11. 6. 5. 4. 3. 2. 1. 8. 7. PPP1R10. 6. 5. 4. 3. 2. 1. 8. 7. TUBB. 6. 5. 4. 3. 2. 1. 8. 7. BAT1. 6. (b). 5. 4. 3. 2. 1. 0. 8. Relative mRNA to those in normal cerebella. 7. Relative mRNA to those in normal cerebella. BAT2. 6. 5. 4.

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Fig. S1

Fig. S1. PBS MSCs NPCs. *. *. *. *. *. PBS MSCs NPC PSA-NCAM +. *. bFGF.

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0 . 5

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18S rRNA

At-SAT3. 18S rRNA. 51. 69. 76. 1. 35. 64. SNN. At-SATa. At-SATi. Suppl. 2 mRNA levels of At-SAT in roots of wild type (SNN) and transgenic tobacco expressing At-SATa or At-SATi

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Relative Slug mRNA levels

A. *. 10. 8. *. 6. Relative Slug mRNA levels. 4. 2. 0. hLef-1. -. -. +. +. 4.1. fold induction. 8.3. hOBs. SaOS-2. B. 6. *. Lef-1. 54 KDa. Slug. 30 KDa. 4. IP(3)K. 85 KDa. Slug/IP(3)K D.U. *. 2. 0. hLef-1. -. -. +. +. fold induction. 1.6. 5. hOBs.

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mRNA levels (arbitrary units)

25. 8. ARO. 6. mRNA levels (arbitrary units). ARO-pCMV. 4. ARO-Pax8 cl.8. ARO-Pax8 cl.21. 2. 0. TPO. Tg. NIS. PDS. TTF1.

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