Photoreactivation - PowerPoint PPT Presentation

Microbial Genetics (Micr340)

Microbial Genetics (Micr340) . Lecture 14 DNA Repair and Mutagenesis. Definitions. Lesion: chemical damage in DNA Mutagens: chemical compounds that cause lesions in DNA which can kill cells and can also increase frequency of mutations in DNA. Evidence for DNA repair.

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The Damage and Repair of DNA

The Damage and Repair of DNA. Two main types of DNA damage: *point mutations *structural changes. The molecular basis of point mutations. 1. Base substitution (mismatches) transition transversion. 2. Tautomeric shift. Gene Mutation. The molecular basis of point mutations.

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358 views • 15 slides

Repairing Damages Bases

Repairing Damages Bases. 1. Mismatch repair (MMR). Dam methylase:. MutS:. Repairing Damages Bases. 1. Mismatch repair (MMR). Repairing Damages Bases. 2. Photoreactivation. Repairing Damages Bases. 3. Repair of alkylation. (BER). Repairing Damages Bases. 4. Base excision repair (BER).

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282 views • 10 slides

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