'Tau protein' diaporamas de présentation

Stem Cell Concept

Stem Cell Concept. Pg. 721. Signal Transduction Pathways and Cell Differentiation. Stem Cell. Specialized cell type (neuron, skin cell, red blood cell, etc.). Blood Cell Formation. Erythropoietin (Epo). (Epo). Red Blood Cell Development. EPO. Synthesis of proteins that

1.59k views • 104 slides

DEMENTIA

DEMENTIA. Prof. Abdulkader Daif Consultant Neurologist 2011. Cognitive Disorders (DSM-IV). 1. Dementia 2. Delirium 3. Amnesic Disorder. Cognition. Brain functions including: Attention Initiation Memory Language Calculation Praxis Executive functions

1.14k views • 57 slides

Protein-Misfolding Diseases PHY6940 April 8 th 2009

Protein-Misfolding Diseases PHY6940 April 8 th 2009. Jessica Nasica. Overview of the presentation. General facts on protein folding Causes of misfolding and protein aggregation Cellular consequences of protein aggregation Protein-misfolding diseases Amyloidoses Amyloid fibril formation

814 views • 41 slides

Neurodegenerative Disorders

629 views • 32 slides

University Hospital of the Saarland

Department of Clinical Chemistry and Laboratory Medicine. University Hospital of the Saarland. Australian Association of Clinical Biochemists Talk, Sydney, April 20th. Role of Phosphorylation and Methylation in Neurodegenerative Diseases (Alzheimer and Parkinson). Wolfgang Herrmann.

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https://www.creative-biogene.com/blog/index.php/2018/06/28/new-finding-reminds-the-further-consideration-of-the-biological-mechanism-of-alzheimers-disease-caused-by-cognitive-decline/

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Tau Phosphorylation

Tau protein is produced by alternative mRNA splicing of a single gene MAPT. Human MAPT is located at the chromosomal locus 17q21 and contains 16 exons, and alternative splicing of exons 2, 3, and 10 yields six isoforms. The structure of tau protein is divided into four regions: an acidic N-terminal region, a proline-rich region, a microtubule-binding domain (MBD) that is responsible for tau binding to microtubules and a C-terminal region.

28 views • 1 slides