'Urea cycle' diaporamas de présentation

MEDICAL BIOCHEMISTRY

MEDICAL BIOCHEMISTRY. Enzyme Kinetics Enzymes are protein catalysts that, like all catalysts, speed up the rate of a chemical reaction without being used up in the process.

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UNIT 2. Structure and function of proteins.

UNIT 2. Structure and function of proteins. OUTLINE. 2.1. Amino acids. Structure. Ionic properties/Acid-base properties Uncommon amino acids. 2.2. Peptides. Primary structure determination. Peptide bond. Nomenclatures of the peptides. Characteristics of the peptides.

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Leukodystrophy

Leukodystrophy. Tyler Reimschisel, MD September 6, 2013. Clinical Presentations of IMD. Intoxication Urea cycle defects Energy Failure Mitochondrial disease Glycogen storage disease Complex Molecule Lysosomal storage disease Glycogen storage disease Peroxisomal storage disorders.

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Detoxification of endogenous and exogenous compounds

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Pediatric Puzzler

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Amino Acid Metabolism 1: Nitrogen fixation and assimilation, amino acid degradation, the urea cycle

Amino Acid Metabolism 1: Nitrogen fixation and assimilation, amino acid degradation, the urea cycle. Bioc 460 Spring 2008 - Lecture 38 (Miesfeld). Glutamine synthetase converts glutamate to glutamine through a nitrogen assimilation reaction.

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Protein

Protein. synthesis. break down. Amino acids. de novo synthesis. Oxidation. Transamination. Muscle. Amino acids. Blood. Alanine Glutamine Glutamate. Schematic protein turnover and metabolic fates. Muscle will not improve with protein feeding alone!.

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PCRRT for Metabolic Disease

PCRRT for Metabolic Disease. Timothy E. Bunchman Professor Pediatrics. Signs and Symptoms of Hyperammonemia. Initially healthy appearing neonate with decompensation after several days Often seen after institution of protein feedings Lethargy Poor feeding Vomiting Hypotonia.

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Amino Acid Metabolism 2: Amino acid biosynthesis, amino acids are metabolites, metabolic genetic disorders

Amino Acid Metabolism 2: Amino acid biosynthesis, amino acids are metabolites, metabolic genetic disorders. Bioc 460 Spring 2008 - Lecture 39 (Miesfeld). Albinism is caused by mutations in the tyrosinase gene which is required for pigment biosynthesis.

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Ruminants....

Ruminants. Feed In. VFA Microbial Protein Vitamins. The nutrients presented to the cow or steer by the rumen are very different than those entering the rumen as feed. Digestion. Fermentation. All CHO must pass through Pyruvate to become VFA. Some Basics.

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Amino Acid Metabolism 2: Amino acid biosynthesis, amino acids are metabolites, metabolic genetic disorders

Amino Acid Metabolism 2: Amino acid biosynthesis, amino acids are metabolites, metabolic genetic disorders. Bioc 460 Spring 2008 - Lecture 39 (Miesfeld). Albinism is caused by mutations in the tyrosinase gene which is required for pigment biosynthesis.

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# 3 UREA CYCLE

# 3 UREA CYCLE. Reactions of the Urea Cycle Enzyme Regulation of the Urea Cycle Nutritional Regulation of Urea Synthesis Urea Cycle Disorders & Treatment. Urea Cycle. 1. GDH is the major agency responsible for ammonium production. 2. Ammonium is toxic (N = 15 - 40 ?M , max 70?M)

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Effects of Solid Feed on Rumen p H and Molecular Adaptations in Dairy Calves

Effects of Solid Feed on Rumen p H and Molecular Adaptations in Dairy Calves. Anne Laarman, M.Sc. Ph.D. Student University of Guelph alaarman@uoguelph.ca. Rumen Development. Protein. Acidotic pressure. Starter. VFAs (incl. butyrate). Epithelium. Rumen Development.

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Carnitine Transport Deficiencies

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Urea cycle

Urea cycle.

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Figure 15.01 Root nodules from clover.

Figure 15.01 Root nodules from clover. Figure 15.02 Model of the FeMo cofactor of nitrogenase. Figure 15.03 The nitrogen cycle. Figure 15.04 E. coli glutamine sythetase. Figure 15.05 PLP-catalyzed transamination. Figure 15.06 Nitrogen metabolism in context. Figure 15.07 Tetrahydrofolate.

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Bioc 460 Spring 2008 - Lecture 38 (Miesfeld)

Amino Acid Metabolism 1: Nitrogen fixation and assimilation, amino acid degradation, the urea cycle. Bioc 460 Spring 2008 - Lecture 38 (Miesfeld). Glutamine synthetase converts glutamate to glutamine through a nitrogen assimilation reaction.

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CHAPTER 20 PROTEIN METABOLISM

CHAPTER 20 PROTEIN METABOLISM. Nitrogen of Amino Acids. nitrogens to be excreted are collected in glutamate which is oxidized to a - ketoglutarate and NH 4 + . The Urea Cycle - Overview. Urea cycle: a cyclic pathway that produces urea from CO 2 and NH 4 + . Amino Acid Catabolism.

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Amino Acids Metabolism 2 nd Year Medicine

Amino Acids Metabolism 2 nd Year Medicine. By Eman Mokbel Alissa, Ph.D. Lecture (1) content. Relationship to central metabolism Nitrogen disposal Transamination (aminotransferases/ transaminases) Glutamate dehydrogenase (amino acid oxidative deamination)

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Sir Hans Adolf Krebs Sheffield University United Kingdom

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