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Performance Characteristics of Six Commercial IgM Tests Relative to the CDC IgM Capture EIA*

Performance Characteristics of Six Commercial IgM Tests Relative to the CDC IgM Capture EIA*. * Assay comparison study was an ARRA-funded project done in conjunction with the APHL Santa Clara County Public Health Department and Iowa State Hygienic Laboratory performed the testing.

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Performance Characteristics of Six Commercial IgM Tests Relative to the CDC IgM Capture EIA*

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  1. Performance Characteristics of Six Commercial IgM Tests Relative to the CDC IgM Capture EIA* *Assay comparison study was an ARRA-funded project done in conjunction with the APHL Santa Clara County Public Health Department and Iowa State Hygienic Laboratory performed the testing.

  2. Measles Specimens Referred to CDC for Confirmatory or Reference Testing – 2006 to 2011

  3. Laboratory Confirmed Measles Cases in USA: 2012 • Measles was laboratory-confirmed in 48 (87%) cases • 20 (42%) by detection of measles-specific IgM antibodies only • 24 (50%) by detection of measles-specific IgM antibodies and measles virus RNA • 4 (8%) by detection of measles virus RNA only National Center for Immunization and Respiratory Diseases Division of Viral Diseases

  4. Laboratory Confirmed Measles Cases in the USA, 2013 with Laboratory Results Shared with CDC • IgM only 32 (45%) • IgM and PCR 26 (37%) • PCR only 12 (17%) • Total 70 National Center for Immunization and Respiratory Diseases Division of Viral Diseases

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