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Endocrine System

Endocrine System

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Endocrine System

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  1. Endocrine System

  2. Endocrine System • Endocrine glands are composed of cells that secrete: • Hormones • amino acid derivatives • peptides and proteins • steroids

  3. Hormones act by attaching to receptors of specific target cells

  4. Function of endocrine system: • homeostasis • growth and development

  5. Endocrine Glands • Hypothalamus • oxytocin production • ADH production • production and secretion of regulatory hormones for anterior pituitary

  6. Pituitary (hypophysis) • posterior pituitary • oxytocin secretion • ADH secretion

  7. Pituitary (hypophysis) • anterior pituitary • Tropic hormones • TSH • ACTH • Gonadotropins: FSH, LH • Prolactin • Growth hormone

  8. all anterior pituitary hormones are regulated by hypothalamic hormones • regulation dependent upon hypophyseal portal system

  9. Thyroid Gland

  10. Thyroid Gland • T4 and T3: released by thyroid follicles • calcitonin: released by C cells

  11. Parathyroid glands

  12. Parathyroid glands

  13. Parathyroid glands • PTH

  14. Adrenal Gland

  15. Adrenal Gland

  16. Adrenal cortex • mineralocorticoids • glucocorticoids • adrenal androgens • Adrenal medulla • E and NE

  17. Endocrine pancreas • Islets of Langerhans • glucagon: from alpha cells • insulin: from beta cells • somatostatin: from delta cells

  18. Pineal gland • melatonin • Heart • ANP • Kidney • renin • EPO

  19. Thymus Gland • thymosin

  20. Reproductive System • Testes • testosterone • inhibin • Ovaries • estrogens • progesterone

  21. Endocrine Disorders • Acromegaly

  22. Endocrine Disorders, continued • Acromegaly • Gigantism

  23. Endocrine Disorders, continued • Acromegaly • Gigantism • Pituitary Dwarfism

  24. Endocrine Disorders, continued • Goiter

  25. Endocrine Disorders, continued • Goiter

  26. Endocrine Disorders • Grave’s disease

  27. Endocrine Disorders, continued • Cretinism

  28. Endocrine Disorders, continued • Cushing’s disease

  29. Endocrine Disorders, continued • Cushing’s disease • Addisons disease

  30. Endocrine Disorders, continued • Type I diabetes • Type II diabetes