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Electron Transport Chain . Introduction . NADH and FADH 2 are __________________ These electrons are transferred to a series of components that are found in the inner mitochondrial membrane This is known as the _________________________________.
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Introduction • NADH and FADH2are __________________ • These electrons are transferred to a series of components that are found in the inner mitochondrial membrane • This is known as the _________________________________
Therefore, before we enter the electron transport chain we have: • ___________ • ___________
The ETC is a series of proteins arranged as a chain on the _______of the inner mitochondrial membrane • The components of the ETC are arranged in order of increasing electronegativity: starts with the _______ attractor of electrons and ends with the _________
Complexes in the ETC • NADH dehydrogenase • Ubiquinone (Co-enzyme Q) • Cytochrome b-c • Cytochrome c • Cytochrome oxidase
NADH passes its electrons on to Complex I – NADH dehydrogenase • FADH2passes its electrons to Q (shuttle)
Proton Pumps • Move protons (H+ ions) from the ______________into the _________________________ • Protons moving ______________(need energy to do this), the __________moving through the complexes provide this energy • A proton gradient is created and the energy powers the ATP synthase enzyme- an ATP pump called an __________ • 3 proton pumps • ___________ • ___________ • ___________
NADH passes its electrons on to Complex I – NADH dehydrogenase • FADH2 passes its electrons to Q (shuttle) How many protons get pumped for every NADH? _______ How many protons get pumped for every FADH2? _______
Final Electron Acceptor • Why do we need oxygen for cellular respiration? • ____________________________________________ • It takes the _____________from the final proton complex (III) (cyctochromeoxidase) and takes _____________from the matrix and forms _______________ 2e- + 2H++ O2 H2O
Chemiosmosis • Protons accumulate in the intermembrane space of the mitochondria this creates an electrochemical gradient • ____________________________________________ H+ (proton)
ATP Synthase • The protons cannot move through the phospholipid bilayer • ________________________________________________________________________________________ • Protons move through the ATPase complex and as a result the synthesis of ATP from ADP and P occur in the matrix
How many ATP are formed? • Start off with 10 NADH: • __________________________ • __________________________ • __________________________ • Start off with 2 FADH2 • ___________________________ • ____________________________
Putting it all together… The Electron Transport Chain: 1. 2. _ _________________________ 3. 4._____________________________